糖尿病合并肺毛霉菌感染的临床分析  

Clinical analysis of diabetes combining with lung thread fungus infection

作　　者：孙文青[1] 孙莹[1] 赵婷婷[1] 周明香[1] 林美英[1] 郭鹏[1] 郭帅[1] 刘春利[1] 

机构地区：[1]山东省胸科医院呼吸四科,山东济南250013

出　　处：《中国医院药学杂志》2008年第16期1377-1378,共2页Chinese Journal of Hospital Pharmacy

摘　　要：目的:探讨糖尿病合并肺毛霉菌感染的防治,减少死亡率。方法:对11例糖尿病合并肺毛霉菌感染的危险因素、临床表现、诊断及治疗进行总结分析。结果:11例糖尿病患者经痰培养临床确诊为肺毛霉菌感染。用两性霉素B治疗大约4周后,9例有效,1例因合并高钾血症转外院透析治疗,1例因合并蛛网膜下出血死亡。结论:毛霉菌病是一种致死率很高的系统性真菌感染性疾病,因此,早期应用两性霉素B治疗是提高糖尿病合并肺毛霉菌病治愈率的关键。OBJECTIVE To approach prevention and treatment for diabetes combining with lung thread fungus infection in order to deceasing mortality rate. METHODS To sunmmarize and analyze the risk factors, clinical manifestation, diagnosis and treatment of 11 diabetic patients combining with lung thread fungus infection. RESULTS The 11 diabetic patients were clinically diagnosed as lung thread fungus infection by sputum culture, and treated with amphotericin B for about 4 weeks. As a result, 9 cases were effective, 1 patient was treated with dialysis because of renal failure with hyperkalemia, and 1 patient died as combining with subarachnoid hemorrhage. CONCLUSION Mucormycosis is the systemic Fungal infectious disease with high mortality rate. Positive blood glucose control and earlier treatment with amphotericin B play a vital role in curing diabetes combining with lung thread fungus infection.

关 键 词：糖尿病 毛霉菌 两性霉素B 

分 类 号：R563.1[医药卫生—呼吸系统] R587.1[医药卫生—内科学]