单手性臂脱氧胆酸分子钳的设计与微波合成  

Design and synthesis of molecular tweezers with single chiral arm derived from deoxycholic acid under microwave irradiation

作　　者：陈静[1] 赵志刚[1] 李晖[1] 严平[1] 

机构地区：[1]西南民族大学化学与环境保护工程学院,四川成都610041

出　　处：《化学研究与应用》2008年第9期1212-1215,共4页Chemical Research and Application

基　　金：西南民族大学博士创新基金资助项目(No.08NBS002)

摘　　要：Eight molecular tweezers with single chiral arm have been synthesized by linking L-amino acid methyl esters to 3-position of methyl deoxycholate via triphosgene under microwave irradiation.The structures of these receptors are characterized by 1H NMR,IR,MS spectra and elemental analysis.Compared with the conventional method,this method is simple,safe,rapid and eco-friendly.Eight molecular tweezers with single chiral arm have been synthesized by linking L-amino acid methyl esters to 3-position of methyl deoxycholate via triphosgene under microwave irradiation. The structures of these receptors are characterized by 1H NMR, IR,MS spectra and elemental analysis. Compared with the conventional method, this method is simple, safe,rapid and eco-friendly.

关 键 词：脱氧胆酸 分子钳 微波辐射 合成 

分 类 号：O641.3[理学—物理化学]