肥胖与非肥胖糖耐量受损患者血清C反应蛋白表达水平的研究  

Study of C-Reactive Protein in Peripheral Blood of impaired glucose tolerance Patients with or without Obesity

作　　者：华瑞芳[1] 舒峤[1] 方卫东[1] 

机构地区：[1]赣南医学院附属市立医院赣州市立医院内分泌科,江西赣州341000

出　　处：《赣南医学院学报》2008年第4期567-568,共2页JOURNAL OF GANNAN MEDICAL UNIVERSITY

摘　　要：目的:探讨肥胖和非肥胖糖耐量受损(IGT)患者血清CRP表达的差异和临床意义。方法:117例IGT患者和68例正常糖耐量(NGT)对照组按BM I≥25kg/m2和BM I<23 kg/m2分为肥胖组与非肥胖组,以免疫散射比浊法测定CRP并加以比较。结果:CRP水平IGT组和NGT组各自组内比较,肥胖者均较非肥胖者高(P<0.05);组间比较,IGT组较NGT组CRP水平在肥胖者和非肥胖者均增高,差异显著(P<0.01)。结论:IGT患者较NGT患者,肥胖较非肥胖者的炎症因子表达更显著。Objective：To discuss the difference in C -reactive protein（CRP） in peripheral blood of impaired glucose tolerance （IGT） patients with or without obesity. Methods： 117 IGT patients and 68 normal glucose tolerance（NGT） patients control group were divided into obesity group（ BMI≥25kg/m^2） and non- obesity group（ BMI 〈 23 kg/m^2）. The level of CRP was dectected by turbidimetric immunoassay . Results： The level of CRP in obesity subjects was significant higher than that in non - obesity subjects in both IGT group and control group （ P 〈 0.05 ）. The level of CRP in Obesity and non - obesity subjects in IGT group were significant higher than NGT group（P 〈 0.01 ）. Conclusion：IGT patients and obesity subjects have more significance in C -reactive protein（CRP） expression than NGT patients and non - obesity subjects, respectively.

关 键 词：肥胖 糖耐量受损 C反应蛋白 

分 类 号：R587.1[医药卫生—内分泌]