滕州市消除淋巴丝虫病的防治对策与效果评价  

Assessment of measure and results in elimination of lymphatic filariasis in Tengzhou City

作　　者：袁克兵[1] 马士学[1] 

机构地区：[1]滕州市卫生防疫站,山东滕州277500

出　　处：《中国热带医学》2008年第10期1696-1698,共3页China Tropical Medicine

摘　　要：目的分析评价滕州市消除淋巴丝虫病的防治对策。方法收集滕州市历年来淋巴丝虫病防治资料,并进行统计分析,评价不同阶段的防治措施及效果。结果防治前(1957年)流行病学调查,人群平均微丝蚴(mf)率为25.3%,慢性丝虫病患病率为5.95%,通过普查普治、重点查治、海群生药化食盐(以下简称"药盐")防治等一系列技术措施,于1975年mf率以行政村为单位均降至1%以下,在全国率先达到了基本消灭丝虫病的标准;丝虫基本消灭后,病原、蚊媒横向监测16年,mf率为0～0.12%,蚊媒幼丝虫自然感染率为0～0.61%,mf率和蚊媒幼丝虫自然感染率自末次病原阳性次年(1985年)起至1991年7年间均降为0。病原、蚊媒及血清学纵向监测16年,mf率、蚊媒幼丝虫自然感染率,在监测第1年时分别为0.43%和0.42%,至第7年后均降至0。人群丝虫抗体阳性率由监测第8年18.42%降至第16年时的5.84%;利用各种有效治疗方法对慢性丝虫病患者进行了系统治疗与照料,丝虫性淋巴水肿、乳糜尿和鞘膜积液的患病率由防治前的5.95%下降至基本消灭后第10年后的0.97%。结论以消灭传染源为主导的综合防治策略尤其采用全民普服海群生"药盐"措施是实现消除丝虫病的关键。Objective To assess the meaures and results in elimination of lymphatic filariasis in Tenchou City. Methods Data concerning the control of lymphatic filariasis in various stages were collected and analyzed. Results The microfilarial rate before antifilarial campaign in 1957） was 25.3% and the incidence of chronic filaariasis was 5.95%. After a serious of control meaures were taken inclduing epidmiological surveys, vector control , mass drug prophylaxis, and tratment with medicated salt （DEC）, the microfilarial rate dropped to below 1%, to be the first province in China to atain the criteria of elimination of lymphatic filariasis. The microfialarial rate was 0 - 0.12% 16 years after longitudinal surveillance and the natural infection of mosquito vectors were 0 -0.61%. The chronic lymphatic filariasis cases were systematically and effectively treated with various means. The incidence of filarial edema, filarial chyluria and hydroedema was reduced from 5.95% before control to 0.97% 10 years after the disease was eliminated. Conclusion The integrated control measures with elimination of source of infection as the main work, especially mass DEC campaign are the main key in attaining the objective of elimination of filariasis in this propvince.

关 键 词：丝虫病 微丝蚴血症 海群生 传染源 纵向监测 横向监测 

分 类 号：R383.16[医药卫生—医学寄生虫学]