三种用药方案预防急性化脓性阑尾炎术后感染的药物经济学评价  

Pharmacoeconomics of 3 prophylactic medication schemes for septic acute appendicitis postoperative infection

作　　者：智勇刚[1] 李静[1] 樊莲莲[1] 李芙蓉[1] 杨飞[2] 彭曦[1] 

机构地区：[1]石河子大学医学院第一附属医院药剂科,新疆石河子832008 [2]石河子大学校医院,新疆石河子832000

出　　处：《农垦医学》2008年第4期271-273,共3页Journal of Nongken Medicine

基　　金：新疆生产建设兵团医药专项基金(2006GG54)

摘　　要：目的:评价3种抗菌药物用药方案预防急性化脓性阑尾炎术后感染的疗效和经济性。方法:采用回顾性调查方法,对我院99例急性化脓性阑尾炎术后预防性应用A组(头孢噻肟+替硝唑)、B组(头孢哌酮舒巴坦钠+替硝唑)、C组(头孢匹胺+替硝唑)进行最小成本分析。结果:3组方案预防急性阑尾炎术后感染的疗效比较无统计学意义(P>0.05),其治疗成本分别为(1 909.36±358.19)元,(2 617.66±396.56)元,(3 490.27±885.96)元。结论:A组为这3组中最佳用药方案。Objective： To evaluate the economic efficacy of three antibacterials prophylactic medication schemes for septic acute appendicitis postoperative infection. Methods： Using the analytical method of retrospective review, a total of 99 patients with septic acute appendicitis were divided into 3 groups： Group A was assigned to receive Cefotaxime plus Tinidazole; Group B to receive Sulbactam ＋ Cefoperazone plus Tinidazole;Group C to receive Cefpiramide plus Tinidazole.All 3 groups carried out cost minimization analysis. Results： Comparison of curative effect was not statistically significan in 3 prophylactic medication schemes for acute appendicitis postoperative infectiont（P 〉 0.05）,against respective costs of 1 909.36 ± 358.19 yuan,2 617.66 ± 396.56 yuan and 3 490.27±885.96 yuan. Conclusion： Scheme C is more cost-effective in acute appendicitis postoperative infection.

关 键 词：急性阑尾炎手术 抗菌药物 预防用药 最小成本分析 

分 类 号：R574.61[医药卫生—消化系统]