多药耐药革兰阴性杆菌qacE△1-sul1基因检测及临床意义  

qacE△1-sul1 Genes in Multidrug-resistant Gram-negative Bacilli and Their Clinic Significance

作　　者：朱健铭 姜如金[1] 吴康乐[1] 吴玲丽[1] 沈跃建 

机构地区：[1]杭州市余杭区中医院检验科,浙江杭州311106

出　　处：《中华医院感染学杂志》2008年第9期1209-1211,共3页Chinese Journal of Nosocomiology

基　　金：杭州市余杭区科技局科研基金资助(2005-12)

摘　　要：目的了解多药耐药革兰阴性杆菌耐qacE△1-sul1基因存在情况,并讨论其临床意义。方法自临床分离225株多药耐药革兰阴性杆菌,采用聚合酶链反应法检测qacE△1-sul1基因。结果225株革兰阴性杆菌qacE△1-sul1基因阳性120株,阳性率53.3%。结论临床分离的革兰阴性杆菌qacE△1-sul1基因携带率较高。OBJECTIVE To investigate the qacEAl-sull genes in multidrug-resistant Gram-negative bacilli and their significance. METHODS A total of 225 strains of multidrug-resistant Gram-negative bacilli were clinically isolated. The genes of qacE△1-sul1 were analyzed using polymerase chain reaction（PCR）. RESULTS From them 120 strains of multidrug-resistant Gram-negative bacilli were found the qacEAl-sull genes. The positive rate of qacE△1-sul1 was 53.3%. CONCLUSIONS There are high percentages of qacE△1-sul1 genes in multidrug-resistant Gram-negative bacilli.

关 键 词：革兰阴性杆菌 消毒剂 基因 

分 类 号：R378[医药卫生—病原生物学]