山东省医院感染监控网葡萄球菌属耐药性分析  

Antimicrobial Resistance of Staphylococcus:Analysis by Shandong Provincial Nosocomial Infection Surveillance System

作　　者：李卫光[1] 祝筠[1] 朱其凤[1] 申翠华[1] 

机构地区：[1]山东省立医院感染管理办公室,山东济南250021

出　　处：《中华医院感染学杂志》2008年第9期1317-1319,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解葡萄球菌属对临床常用抗菌药物耐药性的变化趋势。方法统计分析山东省医院感染监控网2002年1月-2005年12月医院感染病例葡萄球菌属的耐药情况。结果共分离出葡萄球菌属1644株,主要分布于下呼吸道、手术切口、皮肤软组织和泌尿道等,分别占39.72%、22.08%、9.43%和7.54%;葡萄球菌属对临床多种常用抗菌药物呈现耐药,仅对万古霉素等少数抗菌药物敏感。结论葡萄球菌属的耐药问题是抗感染治疗的主要威胁,合理使用抗菌药物和采取有效控制措施是避免医院感染暴发流行的重要措施之一。OBJECTIVE To investigate the trends of susceptibility of Staphylococcus isolates to antimicrobial agents analyzed by the Shandong provincial nosocomial infection surveillance system. METHODS The data from Jan 2002 to Dec 2005 were summarized and analyzed by the Shandong provincial nosoeomial infection surveillance system. RESULTS During this period, 1644 strains of first isolate from each patient were collected. Major specimens were sputum, wounds, skin soft tissue and urine, which were 39. 72%, 22. 08%, 9. 43% and 7. 54% in total specimens, respectively. The drug-resistant rates of Staphylococcus isolates to antimicrobials were high, except to vancomycin. CONCLUSIONS Antimicrobial resistance of clinical isolates threatens the success of infectious disease treatment. It is very important to promote the rational use of antimicrobial agents for control of resistance and to take effective measures for the prevention of infections.

关 键 词：葡萄球菌属 耐药性 分析 

分 类 号：R378.11[医药卫生—病原生物学]