济南市济阳县15～40岁人群乙型肝炎血清流行病学调查  

Seroepidemiological Investigation of Hepatitis B Virus Infection among People Aged 15～40 years in Jiyang County

作　　者：张济[1] 赵小冬[1] 杨华[1] 周志中[1] 韩晓辉[1] 

机构地区：[1]济南市疾病预防控制中心,山东250013

出　　处：《中国预防医学杂志》2008年第9期811-813,共3页Chinese Preventive Medicine

摘　　要：目的了解济阳县乙型肝炎(乙肝)病毒(HBV)感染标志的分布情况。方法2003年11月在济南市济阳县开展了15～40岁人群HBV感染标志分布的横断面调查,共采集合格外周静脉血1994人份。乙肝病毒表面抗原(HBsAg)、乙肝病毒表面抗体(抗-HBs)、乙肝病毒核心抗体(抗-HBc)均用固相放射免疫(SPRIA)法检测。结果15～40岁人群HBsAg、抗-HBs、抗-HBc和HBV感染率分别为6.52%、24.77%、30.99%和43.63%。HBsAg感染率随年龄的增长而升高,HBsAg感染率在男女之间的差异无统计学意义。结论济阳县15～40岁人群HBsAg的阳性率仍处于较高水平,提示我们未来应加强儿童乙肝疫苗计划免疫的同时,加强高危人群和成人的预防接种工作。Objective To understand the prevalence of hepatitis B virus （HBV） markers among people aged 15 -40 years in Jiyang county. Methods A cross sectional study was carried out. 1 994 qualified peripheral venous blood samples were collected, HBsAg, anti -HBs and anti - HBc were tested by solid phase radioimmunoassay. Results The infectious rates of HBsAg, anti - HBs, anti - HBc and HBV were 6. 52% , 24. 77%, 30.99% and 43.63% respectively. The HBsAg positive rate rose with aging. There was significant difference in HBsAg rate between male and female. Conclusion The positive rate of HBsAg was in high level in Jiyang. The inoculation of HBV vaccine should be expanded and enhanced among both children and high - risk people and adults.

关 键 词：乙型肝炎 血清流行病学 感染标志 

分 类 号：R512.62[医药卫生—内科学] R181.3[医药卫生—临床医学]