本院103例药品不良反应报告分析  

Adverse Drug Reactions: Analysis of 103 Cases in Our Hospital

作　　者：肖佩玉[1] 宋湘芝[1] 宋伟峰[1] 卢惠敏[1] 

机构地区：[1]中山大学附属第三医院药剂科,广东广州510630

出　　处：《广州医学院学报》2008年第2期68-71,共4页Academic Journal of Guangzhou Medical College

摘　　要：目的：分析本院药品不良反应（ADR）发生的特点与一般规律。方法：收集本院2007年1月-2007年6月上报的103例ADR报告，从患者年龄、性别、药品种类、给药途径、涉及器官或系统以及临床表现等方面进行统计、分析。结果：103例ADR报告中，抗感染药物引发ADR的比例最高（57．14％）；20～29岁患者ADR的发生率最高（33．98％）；静脉给药方式引发ADR发生率最高（73．79％）；ADR的临床表现以皮肤及附件损害为主（69．81％）。结论：合理使用抗感染药，以避免或减少ADR的发生，加强ADR监测意识，确保临床安全、有效、合理地用药．Objective： To analyze the characteristics and general patterns of adverse drug reactions （ADR） in our hospital. Methods： From Jan 2007 to Jun 2007, 103 cases with ADR in our hospital were analyzed statistically in respect of the patients＇ age, sex, drug categories, routes of administration, organs and systems involved, and clinical manifestations. Results： Of the 103 ADR cases, 57.14% were induced by anti-infective agents, 33.98% occurred in patients aged between 20 to 29 years, and 73.79% received the drugs intravenously. Lesions of the skin and its appendages were the main manifestations of ADR, which involved 69.81% of the cases. Conclusion： Anti-infective drugs should be used rationally to awoid or reduce the incidence of ADR. ADR monitoring should be strengthened to ensure safe, effective and rational use of drugs in clinics.

关 键 词：药品不良反应 抗感染药 报告分析 

分 类 号：R969.3[医药卫生—药理学]