舒芬太尼皮下PCA用于术后镇痛的可行性研究  

The Analgesic Effect of Subcutaneous PCA with Sufentanil after Microvascular Decompression of Facial Nerve.

作　　者：唐贞申[1] 张兵[2] 安建雄[2] 马银娜[2] 冷火萍[2] 梅晓辉[2] 张炳熙[1] 

机构地区：[1]首都医科大学附属北京同仁医院麻醉科,100730 [2]清华大学玉泉医院麻醉与疼痛医学科

出　　处：《医学研究杂志》2008年第9期49-51,共3页Journal of Medical Research

摘　　要：目的研究经皮下舒芬太尼病人自控镇痛(PCSA)用于面神经显微血管减压术(MVD)病人的疗效、安全性及其可行性。方法选择MVD患者62例,随机分为舒芬太尼病人自控皮下镇痛组(PCSA组,30例)与病人自控静脉镇痛组(PCIA组,32例)。于手术结束时放置PCA泵并注射负荷量,记录术后1h、6h、12h、24h、48h、72h各时间点的疼痛评分、镇静评分、生命体征、不良反应以及PCA需求按压和有效按压次数及结束PCA后患者总体满意度。结果两组患者各时间点间镇痛镇静评分无显著性差异(P>0.05);各时间点间需求按压和有效按压次数无显著性差异(P>0.05);两组并发症发生率无显著性差异(P>0.05);结束PCA后两组患者总体满意度均较高,组间无显著性差异(P>0.05)。结论舒芬太尼PCSA和PCIA镇痛镇静效果及不良反应无显著性差异,而PCSA更简便实用。Objective To investigate the clinical efficacy, safety and availability of subcutaneous PCA with sufentanil after micro- vascular decompression （MVD） of facial nerve. Methods All 62 patients with hemifacial spasm were divided randomly into Patient - Controlled Subcutaneous Analgesia（PCSA） group （ n = 30 ） and Patient - Controlled Intravenous Analgesia （ PCIA ） group （ n = 32 ） after MVD of facial nerve. PCSA or PCIA with sufentanil was administered after MVD. The following variables were recorded at time intervals of 1, 6, 12, 24, 48, 72h after the administration of PCA. Results There were no significant differences between two groups in terms of the visual analogue scale（VAS） , sedation score, complications and patient satisfaction（P 〉 0.05）. Conclusion PCSA with sufentanil is an same effective analgesic way as PCIA. However, PCSA is simple, easy, able to provide longer possible time if the subcutaneous catheter be correctly placed.

关 键 词：面神经显微血管减压术 病人术后自控镇痛 皮下注射 静脉注射 舒芬太尼 

分 类 号：R614.43[医药卫生—麻醉学] R614.24[医药卫生—外科学]