Toxoplasma gondii Mei2序列的电子延伸与分析  

Electronic-extention and analysis of Mei2 in Toxoplasma gondii

作　　者：黄云鹏[1] 夏晓峰[1] 柯崇榕[1] 黄钦耿[1] 江贤章[1] 田宝玉[1] 黄建忠[1] 

机构地区：[1]福建师范大学工业微生物教育部工程研究中心,福州350108

出　　处：《生物信息学》2008年第3期102-105,共4页Chinese Journal of Bioinformatics

摘　　要：Mei2是调控细胞分裂过程的重要蛋白,利用电子延伸技术对Toxoplasma gondiiEST数据库中的Mei2同源的ESTs进行了电子延伸,得到3836bp的Mei2同源电子延伸物,利用ORF Finder预测的相应的编码物为496个氨基酸的Mei2-predict protein,对该蛋白质的理化性质及结构进行了相关的预测与分析,结果显示T.gondii来源的Mei2-predict protein含有一个RBD结构域。系统发育分析表明Mei2-predict protein与Plasmodium来源的Mei2亲源关系最近。Mei2 is an important protein which acts as a regulator involved in meiosis process, we use the electronic- extenfion technology to extend the ESTs from Toxoplasma gondii EST database which homologous with Mei2. And we obtain 3836bp length eontig, it was predicted as encoding a 496 - amino acid length protein- ＂Mei2- predict protein＂. Then the bioinformatical prediction and analysis of protein structure are processed,the study showed that an RBD domain are contained in Mei2- predict protein. The following phylogenefic analysis of Mei2 - predict protein in our study showed that the Mei2- predict protein from T. gondii is similar to the Mei2 protein which was identified from Plasmodium.

关 键 词：电子延伸 Mei2 序列分析 系统发育分析 

分 类 号：Q51[生物学—生物化学]