^(125)I粒子组织间植入治疗腹腔实质性脏器恶性肿瘤的临床观察  

Clinical observation of ^(125)I interstitial brachytherapy for abdominal malignant tumor

作　　者：刘士会[1] 陈虎[1] 吕良峰[1] 

机构地区：[1]安徽省蚌埠市第一人民医院普外科,233000

出　　处：《蚌埠医学院学报》2008年第5期537-539,共3页Journal of Bengbu Medical College

摘　　要：目的:探讨放射性125I粒子组织间植入治疗腹腔实质性脏器恶性肿瘤的应用价值。方法:原发性和转移性肝癌5例,在CT引导下组织间植入125I粒子;4例胰腺癌和1例转移性肝癌在开腹术中超声引导下组织间植入125I粒子。随访1~12个月观察疗效。结果:10例均顺利完成粒子植入,技术成功率100%;5例术前有疼痛病史,术后临床疼痛症状明显改善,无严重并发症;术后2个月CT观察肿瘤体积均有不同程度缩小,有效率达90%。结论:放射性125I粒子组织间植入治疗腹腔实质性脏器恶性肿瘤能有效缓解症状,提高患者生活质量。Objective：To assess the clinical observation of radioactive 125I seeds interstitial brachytherapy for abdominal malignant tumors. Methods：Five patients with primary and metastatic liver cancer received 125I seeds interstitial brachytherapy under CT. Four cases of pancreatic cancer and 1 ease of metastatic liver cancer were treated with 1251 interstitial braehytherapy during laparotomy under outrasound guidance, and the follow-up lasted for 1 - 12 months. Results：The implanting was successfully in all the 10 cases. The pains were relieved obviously in 5 caes and no severe complications were observed. CT showed that the volume of the malignant tumors decreased to some extent during the 2-month follow-up,with an overall response rate of 90%. Conclusions：Radioactive seeds interstitial brachytherapy may relieve the symptoms of patients with abdominal malignant tumors and improve their life quality.

关 键 词：肿瘤/放射疗法 近距离放射疗法 125I 

分 类 号：R730.55[医药卫生—肿瘤]