应用复合中草药提取物对IBD中等毒力活疫苗免疫增强作用的研究  

Immunopotentiation Effect of Compound Chinese Herbal Medicine Extraction on the IBD Live Vaccine of Medium Toxicity

作　　者：刘文利[1] 赵德明[1] 

机构地区：[1]中国农业大学动物医学院,北京100094

出　　处：《动物医学进展》2008年第9期35-41,共7页Progress In Veterinary Medicine

摘　　要：选用两种在山东省普遍使用的中等毒力IBD活疫苗,将240只试验用商品鸡随机分成12组,分别在12日龄和19日龄两次免疫,同时在11日龄时用复合中草药提取物饮水,连用7 d,二免后13 d人工接种vvIBDV,连续观察14 d。结果表明,无论从抗体水平、囊指数、BBIX值、B淋巴细胞EAC花环形成率、T淋巴细胞α-醋酸萘酯酶素(ANAE)阳性率、红细胞(RBC)免疫黏附功能,还是从病理组织学检查、临床保护率、病理保护率等指标来看,都充分表明该复合中草药提取物对中等毒力IBD活疫苗具有显著的免疫增强作用,而且对提高法氏囊等免疫器官的保护作用及疫苗对其损伤后的修复作用也有显著效果。240 commercial chickens at 12-day-age and 19-day-age respectively were immunized with two commercial vaccines of moderate virulent that generally used in the Shandong province were divided into 12 groups and were challenged with vvIBDV after 13 days of the second immunization, at one time, the controlled chickens of 11-day-age drinked water mixed compound Chinese herbal medicine extraction. The experimental results indicated that Chinese herbal medicine extraction can not only strengthen very effectively immunity of infectious bursal disease intermediate vaccine but also alleviate the lesion of IBD attenuated vaccine to chicken immune organs and promote the repairation of the lesion and speedy growth of chicken immune organs.

关 键 词：复合中草药提取物 中等毒力IBD活疫苗 IBDV超强毒 保护率 

分 类 号：S852.659.4[农业科学—基础兽医学] S852.5[农业科学—兽医学]