198株黏液罗氏菌的临床分离情况及耐药性分析  

Analysis of isolated ratio and drug resistance of 198 strains of Rothia mucilaginosus from clinical specimens

作　　者：金艳 张春和 陈东科[2] 马金群 

机构地区：[1]沧州市人民医院检验科,河北沧州061000 [2]卫生部北京医院检验科,北京100730

出　　处：《检验医学》2008年第5期494-496,共3页Laboratory Medicine

摘　　要：目的对黏液罗氏菌的分离率进行统计,并对其耐药性进行分析。方法用常规方法对临床分离的198株黏液罗氏菌进行鉴定。药敏试验采用纸片扩散法,并用E-test药敏条作对照。结果黏液罗氏菌的临床分离率为13%,临床可选择的药物为头孢曲松、利福平、四环素、万古霉素,本菌对环丙沙星、苯唑西林、复方磺胺甲口恶唑均高度耐药。结论对于经常使用抗菌药物、免疫力低下及长期住院的危重患者,黏液罗氏菌是一种重要的机会致病菌,由于耐药菌株的不断出现,建议临床根据药敏试验结果选用抗菌药物。Objective To make statistics of the isolated ratio and analyze the drug resistance of Rothia mucilaginosus. Methods 198 strains of Rothia mucilaginosus were identified with routine method. Drug resistance was analyzed by the disk diffusion method with the E-test method as control. Results The isolated ratio of Rothia mucilaginosus was 13%. The Rothia mucilaginosus were sensitive to ceftriaxone, rifadin, tetracycline, vaneomycin and highly resistant to ciprofloxacin, oxacillin and sulfamethoxazole. Conclusions Rothia rnucilaginosus is an important opportunistic pathogen for the long-term hospitalized patient usually used antibiotincs and with hypoimmunity. It is important to select antibiotics based on the results of the drug sensitivity of the pathogens, because the occurrence of the drug resistant strains increases.

关 键 词：黏液罗氏菌 分离率 耐药性 

分 类 号：R446.5[医药卫生—诊断学]