应用Amplatzer血管塞封堵动脉导管未闭及初步疗效评价  

Transcatheter Closure of Patent Ductus Arteriosus by Amplatzer Vasucular Plug With the Priliminary Effect Evaluation

作　　者：张戈军[1] 蒋世良[1] 凌坚[1] 赵世华[1] 黄连军[1] 徐仲英[1] 金敬琳[1] 吕建华[1] 吴文辉[1] 

机构地区：[1]中国医学科学院北京协和医学院心血管病研究所阜外心血管病医院放射科,北京市100037

出　　处：《中国循环杂志》2008年第4期260-262,共3页Chinese Circulation Journal

摘　　要：目的:应用 Amplatzer 血管塞封堵动脉导管未闭(PDA)并对其疗效进行评价。方法:全组共11例,年龄4.0～17.0(10.09±5.17)岁,体重15～63(35.05±16.20)kg。PDA 长度为8.4～20.9(14.09±3.50)mm,最狭窄处均位于肺动脉侧,直径为1.0～2.0(1.48±0.35)mm;经导管置入 Amplatzer 血管塞封堵PDA。封堵后5～10 min 行胸主动脉造影评价疗效,术后24 h、1个月、3个月及1年进行随访观察有无残余分流及再通。结果:全组技术成功率为100%,无任何并发症。术后10 min 胸主动脉造影示11例动脉导管均完全闭合,无残余分流;5例完成1年随访,PDA 完全闭合,未见再通。结论:应用 Amplatzer 血管寨封堵类似于长管状的 PDA 是一种安全、有效的非手术方法,技术成功率高,即刻效果好,近、中远期随访疗效可靠。Objective ：To conduct transcatheter closure of patent ductus arteriosus （PDA） by Amplatzer vascular plug and to preliminarily evaluate the safety and effect of the treatment. Methods ： A total of 11 PDA patients with the mean age of 10. 09 ± 5. 17 years （ ranging from 4. 0 to 17.0 years） and the mean body weight of 35.05 ± 16.20 kg（ ranging from 15 to 63 kg）were occluded by Amplatzer vascular plug. The length of PDA were 8.4 - 20. 9 （ 14. 09 ± 3. 50） mm, the most narrow spots were at the side of pulmonary artery with the diameter of 1.0 - 2.0 （ 1.48 ± 0. 35 ） mm. Aortography was performed to evaluate the effect of 5-10 minutes after the procedure. Echocardiography was performed at 24 hours,one month,three months and 1 year after the closure to examine whether there was residual shunt and recanalization. Results：The technical successful rate was 100% without complications. Aortography revealed there were complete occlusion without residual shunt in all 1 lcases at 10 minutes after the procedure. One year follow up was done in 5 patients and no residual shunt observed. Conclusion ：Transcatheter closure of PDA with Amplatzer vascular plug was a safe and effective method ,it has the high successful rate with the complete closure immediately after the procedure ;the short and mid-term follow-up showed a good result as well.

关 键 词：动脉导管未闭 介入治疗 Amplatzer血管塞 

分 类 号：R541[医药卫生—心血管疾病]