正二十二烷醇的热力学性质  

Thermodynamic Properties of 1-Docosanol

作　　者：童波[1] 谭志诚[1] 王韶旭[2] 

机构地区：[1]中国科学院大连化学物理研究所热化学实验室,辽宁大连116023 [2]大连交通大学环境与化学工程学院,辽宁大连116028

出　　处：《物理化学学报》2008年第9期1699-1702,共4页Acta Physico-Chimica Sinica

基　　金：国家自然科学基金(20373072)资助项目

摘　　要：用精密自动绝热量热仪测定了广谱抗病毒药物正二十二烷醇在78-400K温区的热容.根据实验测定的热容数据,用最小二乘法拟合计算出热容对温度的多项式方程,得到其相变温度、相变焓、相变熵分别为340.844K、85.07kJ·mol-1、249.6J·K-1·mol-1.根据热力学函数关系式计算了其在80-400K温区每隔5K的热力学函数[HT-H298.15]和[ST-S298.15].用DSC、TG热分析技术进一步考查了该物质在400-900K的热稳定性.Heat capacity Cpm of 1-docosanol was precisely measured in the temperature range from 78 to 400 K by means of an automated adiabatic calorimeter. The dependence of heat capacity on the temperature was fitted to polynomial equations with least square method. The melting temperature, molar enthalpy, and molar entropy of fusion were determined to be 340.844 K, 85.07 kJ· mol^-1, and 249.6 J· K^-1· mol^-1, respectively. The thermodynamic functions, [HT-H298.15] and [ST-S298.15], were derived from the thermodynamic equations in the temperature range from 80 to 400 K with an interval of 5 K. The thermostability of the compound was further investigated by DSC and TG techniques from 400 to 900 K.

关 键 词：正二十二烷醇 热容 DSC TG 热力学性质 

分 类 号：O623.41[理学—有机化学]