不孕症患者病因调查分析  

Investigation on Etiological Factors of Infertile Couples

作　　者：白婷[1] 肖红梅[1] 卢光琇[1] 

机构地区：[1]中南大学湘雅医学院生殖与干细胞工程研究所,中国湖南长沙410078

出　　处：《生命科学研究》2008年第3期267-271,共5页Life Science Research

摘　　要：为探讨及分析不孕不育病因情况,收集3777对门诊初诊患者的年龄、月经史、孕产史及与不孕不育相关的检查结果等资料进行统计分析,结果表明,导致女性不孕的主要病因为输卵管及盆腔疾病,其次为排卵异常,包括多囊卵巢综合征,卵巢早衰等.导致男性不育的主要因素是精液的数量及质量异常,无精子症患者在男性不育患者中占主要比重,其次为少弱畸精子症及严重少弱畸精子症.在无精子症患者中,生精功能障碍为其主要致病因素,先天性输精管缺如也是导致无精子症的重要影响因素.精液异常患者中遗传缺陷是男性不育重要的致病因素之一.In order to explore the common causes correlated with infertility, data of 3 777 couples who diagnosed in outpatient department were collected, including age, menstrual cycle, childbearing history and examinations about infertility and sterility. The statistics showed that tubal and pelvic diseases were the major etiological factors in female. Disorder of ovulation elicited by various reasons was the second cause, which included polycystic ovary syndrome （PCOS）, premature ovarian failure （POF） and so on. Abnormalities of quality and quantity of spermatozoon were the major cause inducing male infertility. Azoospermia occupied a large proportion in infertility male. Then went was oligo-asthenospermic and severe oligo-asthenospermic patients. In azoospermic patients, spermatogenesis failure is the chief etiological factor. Congenital absence of the vas deferentia also took an important place. Anomaly of chromosome and gene could cause male infertility and sterility.

关 键 词：不孕不育 病因 遗传缺陷 

分 类 号：R711.6[医药卫生—妇产科学]