2005年～2007年海淀区麻疹风疹疑似病例抗体测定结果分析  

Analysing results of IgM antibody in suspected measles and rebulla cases in Haidian District of Beijing during 2005～2007

作　　者：韩喜荣[1] 刘洪喜[1] 陈玉峰[1] 

机构地区：[1]北京市海淀区疾病预防控制中心,北京100080

出　　处：《中国卫生检验杂志》2008年第9期1842-1844,1860,共4页Chinese Journal of Health Laboratory Technology

摘　　要：目的：对2005年-2007年海淀区麻疹、风疹疑似病例进行IgM抗体检测,通过结果分析麻疹、风疹流行特征,为其预防及控制提供依据及对策。方法：采用抗体捕捉酶联免疫吸附试验（ELISA）对2005年-2007年麻疹、风疹疑似病例血清标本IgM抗体进行检测;结果用SPSS15.0统计软件进行统计分析。结果：3年麻疹IgM抗体总阳性率42.6%,风疹IgM抗体总阳性率19.1%;麻疹、风疹阳性年龄主要分布在1-40岁,高发年龄为21-30岁;麻疹2007年阳性率明显低于其它2年（χ^2=146.94,P〈0.01）,风疹2007年阳性率明显高于其它2年（χ^2=144.62,P〈0.01）;麻疹IgM抗体阳性病例主要为外来病例,占全部阳性病例的57.2%。结论：海淀区麻疹2006年高发、2007年低发,说明对此病控制有力;对2007年风疹的高发应引起足够的重视,以采取有效的措施加以控制;二者发病年龄逐步后移,21-30岁为一个发病高峰,中小学、大中专院校及青工聚集地逐步成为麻疹、风疹发病的主要群体,建议及时在此年龄段补种“麻风腮联合疫苗”;加强对流动人口的管理,开展查漏补种工作,有效控制流动人口麻疹、风疹的流行。Objective：Testing IgM antibody of measles and rebulla in Haidian District of Beijing during 2005-2007 to analyse the epidemic features and provide strategies for those prevention and control.Methods：IgM antibody was measured by IgM-capture ELISA in all suspected measles and rebulla cases between 2005-2007.The results were analyzed using SPSS15.0 software package.Results：The overall positive rate of IgM in measles and rebulla were 42.6% and 19.1%,respectively.Patients were between 1-40 years old.The incidence was higher between 21-30 years old.The positive rate of measles in 2007 was significantly lower than other two years（χ^2=146.94,P〈0.01） and the positive rate of rebulla in 2007 was significantly more than other two years（χ^2=144.62,P〈0.01）.57.2% of Patients with measles came from places out of Beijing.Conclusion：The control of measles is very impactful,due to the incidence of measles in 2006 is much lower than that in 2007.On the other hand attention must be paid to the rising frequence of rebulla in order to take effective measures to control it.Patients are older step by step and the peak of incidence is between 21-30 years old.The main groups taken measles and rebulla focus on middle and primary school,university and assembling place of young people.Inoculation of ＂Associated immunization of Measles rebulla Parotitis＂ should be taken during these ages.We should be strengthened the management of floating people and the routine immunization services in order to prevent and control measles and rebulla.

关 键 词：麻疹、风疹疑似病例 流行特征 IGM抗体 

分 类 号：R511.1[医药卫生—内科学]