药物冲洗加灌注治疗炎性乳头溢液的初步体会  

A tentative experience for the treatment of inflammatory galactorrhea with pharmaceutical irrigation and perfusion

作　　者：尚延海[1] 张凤霞[1] 冯鑫至[1] 

机构地区：[1]山东省医学影像学研究所乳腺诊疗中心,山东济南250021

出　　处：《医学影像学杂志》2008年第9期987-989,共3页Journal of Medical Imaging

摘　　要：目的:探讨药物冲洗加灌注治疗炎性乳头溢液的价值。方法:随机搜集经纤维乳导管镜检查证实的炎性乳头溢液患者67例,其中单纯乳导管炎患者18例,乳导管炎并导管扩张43例,闭塞性乳导管炎3例,导管积乳并炎症3例。对青霉素过敏实验阴性者应用0.2%甲硝唑注射液冲洗患乳导管加青霉素注射液导管内灌注治疗;对青霉素过敏实验阳性者应用0.2%甲硝唑注射液冲洗加盐酸林可霉素注射液导管内灌注治疗。结果:67例患者中62例接受0.2%甲硝唑注射液冲洗加青霉素注射液灌注治疗,5例青霉素过敏试验阳性者接受了0.2%甲硝唑注射液冲洗加盐酸林可霉素注射液灌注治疗。患者经治疗后3个月随访,18例单纯乳导管炎与3例导管积乳并炎症全部治愈,治愈率100%。乳导管炎并导管扩张43例,36例治愈,治愈率83.72%,闭塞性乳导管炎3例,症状均有所减轻。对所有乳导管炎性疾患的治愈率85.07%(57/67),治疗有效率100%。结论:以0.2%甲硝唑注射液冲洗炎性溢液乳导管加青霉素注射液灌注为治疗乳导管炎性疾患的新途径,治愈率较高,效果肯定。Objectlve：To investigate the value of pharmaceutical irrigation and perfusion in the treatment of inflammatory galactorrhea. Methods：67 patitents with inflammatory galactorrhea diagnosed by fiberoptic ductoseopy were collected randomly, in which 18 eases were simplex mammary duct infection, 43 cases were mammary duct infection incorporated with lactiferous duct ectasia, 3 cases were occlusive mammary duct infection, and 3 cases were duct galactic accumulation complicated with infection. For the negative results of penicilin sensitive test, the patients were treated with 0.2% metronidazole irrigation and penicillin intraduetal peffusion, wide, the patients with positive results were treated with 0.2% metronidazole irrigation and lineomycin hydrochloride intraductal peffusion. Results： Among those 67 patients, 62 cases were treated with 0.2% metronidazole irrigation and penicillin intraductal peffusion, the other 5 cases with positive penicillin sensitive test were received treatment of 0.2% metronidazole irrigation and lineomycin hydrcchloride intraductal perfusion. Follow-up were conducted three months after treatments. Those 18 cases of simplex mammary duct infection and 3 cases of duct galacta accumulation complicated with infection fully recovered （100%）, 36 cases of those 43 patients of mananary duct infectious incorporated with laetiferous duct ectasia recovered （83.72%）, as for those 3 cases of occlusive mammary duct infection, remission of the symptoms were all observed. Conclusion：Treatment with 0.2% metronidazole irrigation and penicillin intraductal peffusion is a new approach to treat inflammatory galactorrhea, which Ires a higher cure rate and positive therapeutic effect.

关 键 词：药物灌注 治疗 炎性乳头溢液 

分 类 号：R814.4[医药卫生—影像医学与核医学] R655.8[医药卫生—放射医学]