急性脑梗死早期高压氧治疗疗效观察  

Effects of hyperbaric oxygen on acute cerebral infarction in early period

作　　者：陆磊[1] 薛波[1] 施弘[1] 孙晓江[1] 张进[1] 

机构地区：[1]上海交通大学附属第六人民医院神经内科,上海200233

出　　处：《中华航海医学与高气压医学杂志》2008年第4期219-221,共3页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

摘　　要：目的研究早期应用高压氧治疗急性脑梗死的疗效和安全性。方法90例确诊为首次发病的急性前循环脑梗死患者分为2组，每组45例。高压氧组在发病后12h内开始进行高压氧治疗，对照组不进行高压氧治疗。结果治疗后第14、28、90天，2组患者的神经功能缺损评分和13常生活能力评分均有改善，高压氧组较对照组提高明显（P〈0．05），2组均未发生严重不良事件。结论0．22MPa高压氧治疗首次发病的急性前循环脑梗死患者，在发病后12h以内，能改善患者神经功能缺损，提高日常生活能力。同时，高压氧对急性脑梗死的治疗是安全的。Objective To explore the effect and safety of hyperbaric oxygen （HBO） therapy on acute cerebral infarction in early period. Methods Ninty patients with first-time acute anterior cerebral infarction were randomly assigned into two groups and 45 patients were in each group. HBO group were treated with HBO within 12 hours, while control group were not treated with HBO. Results At 14,28 and 90 days after treament, NOS（neuro-defieit score） and score of ADL （activities of daily living） in HBO group were higher than those in control group（P 〈0.05）. There were no serious adverse effects in the two groups. Conclusions HBO treatment can improve NOS and ADL of patients with acute cerebral infaretion in 12 hours at O. 22 MPa. At the same time, HBO therapy is safe to acute cerebral infarction.

关 键 词：高压氧 脑梗死 神经功能缺损 日常生活能力 

分 类 号：R686[医药卫生—骨科学]