^99mTc-ECD脑血流灌注显像评估学校恐怖症患儿脑血流差异  

Assessment of cerebral blood flow with ^(99m)Tc-ECD perfusion imaging for children with school phobia

作　　者：高秀丽[1] 余永利[1] 金常青[1] 钱昀[2] 杜亚松[2] 

机构地区：[1]上海交通大学第六人民医院核医学科,上海200233 [2]上海市精神卫生中心心理咨询中心,上海200030

出　　处：《上海交通大学学报（医学版）》2008年第9期1157-1160,共4页Journal of Shanghai Jiao tong University:Medical Science

摘　　要：目的分析评估学校恐怖症患儿性别、年龄组的局部脑血流灌注(rCBF)差异。方法研究组为20例学校恐怖症患儿,男12例,女8例,年龄11~18岁,平均(14.2±2.1)岁,分别进行99mTc-ECD脑血流灌注显像,采用半定量方法分析不同性别、年龄组rCBF的变化。结果男女两组右侧额顶叶、右侧枕叶、左右尾状核+壳核、左丘脑+海马、左右颞枕叶的组间有统计学差异(P<0.05)。未见研究组年龄与PI值有相关性(P>0.05),研究组年龄≥15岁者各脑区的PI与<15岁者的差异只有左侧颞顶叶有统计学意义(P<0.05)。结论99mTc-ECD脑血流灌注显像对学校恐怖症流行病学研究及治疗有一定的帮助。ObjectiveTo explore the clinical and epidemiological value of semi-quantitative regional cerebral blood flow （rCBF） imaging in children with school phobia. Methods A total of 20 cases diagnosed with school phobia were examined with rCBF. Twelve were males and the other 8 were females. The mean age was （ 14.2 ± 2. 1 ） years （ 11-18 years）. Semi-quantitative analysis methods were used to investigate the correlations among gender, age and rCBF. Results There were significant differences in the rCBF of right fronto-parietal lobe, right occipital lobe, caput and putamen, left thalamus and hippocampus, and temporo-occipital lobe between males and females （P 〈 0.05）. There was no relationship between pnrfusion index （PI） and age （P 〉0.05）. Only the PI of left temporo-parietal lobe of those ≥ 15 years old was significantly different from that of those 〈 15 years old （ P 〈 0. 05 ）. Conclusion ^99m Tc-ECD rCBF perfusion imaging plays a role in the study of epidemiology and treatment of school phobia.

关 键 词：学校恐怖症 脑血流灌注显像 放射性核素 

分 类 号：R817.4[医药卫生—影像医学与核医学]