超短波和胸壁振动辅助治疗对轻、中度儿童哮喘诱导痰EOS及血清ECP的影响  

The effects of ultrashortwave irradiation and chest-wall vibration therapy on serum eosinophil cationic protein and the percentage of eosinophil in the sputum of children with asthma

作　　者：赵飞[1] 乔艳红[1] 刘丰[1] 王一彪[1] 

机构地区：[1]山东大学第二医院儿科,济南250033

出　　处：《中华物理医学与康复杂志》2008年第8期546-548,共3页Chinese Journal of Physical Medicine and Rehabilitation

摘　　要：目的探讨超短波和胸壁振动辅助治疗儿童哮喘对诱导痰嗜酸粒细胞百分数（EOS％）、血清嗜酸粒细胞阳离子蛋白（ECP）及肺通气功能的影响。方法68例哮喘儿童随机分为对照组和治疗组，对照组采用常规治疗，治疗组除常规治疗外，先后行超短波和胸壁振动辅助治疗，并分别于治疗前、后采血测ECP，行肺通气功能检查及诱导痰EOS％分类。结果哮喘儿童诱导痰EOS％、血清ECP与肺通气功能指标第1秒最大呼气量占预计值的百分数（FEV，。％）及呼气峰流速占预计值的百分数（PEF％）均呈显著负相关（P〈0．01）；与对照组比较，治疗后治疗组血清ECP、诱导痰EOS％均显著降低，FEV10％、PEF％显著升高（P〈0．05或0．01）。结论超短波和胸壁振动辅助治疗儿童哮喘具有减轻气道炎症和气道受阻、提高肺通气功能的作用。Objective To study the effect of ultrashortwave irradiation and chest-wall vibration therapy on serum eosinophil cationic protein （ECP） and percentage of eosinophil （ EOS% ） in the sputum of children with mild to moderate asthma. Methods A total of 68 children with asthma were divided into a control group and a treatment group. The control group was treated with conventional treatment only, while the treatment group was giv- en ultrashortwave irradiation and chest-wall vibration therapy in addition to the conventional treatment. The serum ECP, EOS% in induced sputum, FEV~ 0ck , and PEF% were measured before and after treatment. The relation- ships among ECP, EOS% , FEVL0% and PEF% were analyzed. Results FEV~.0% and PEF% were negatively correlated with serum ECP and EOS% in children with asthma. Compared with the control group, ECP and EOS% were significantiy reduced after treatment, while FEV~ 0% and PEF% were significantly elevated. Conclusion Ultrashortwave irradiation and chest-wall vibration therapy can improve ventilation by ameliorating airway inflamma- tion and obstruction.

关 键 词：哮喘 超短波 振动 嗜酸粒细胞阳离子蛋白 

分 类 号：R725.6[医药卫生—儿科]