实验性糖尿病大鼠的血浆ATⅡ与C肽变化及糖心宁对其影响的实验研究  

The Changes of the Levels of Plasma AT Ⅱ and C Peptide in the Rat with Experimental Diabetes and the Influence of Tangxinning over Them

作　　者：李德伟[1] 任恩发[1] 孙红梅[1] 白丽敏[1] 吴海霞[1] 许红[1] 魏执真[2] 易京红[2] 周燕青 

机构地区：[1]北京中医药大学,北京100029 [2]北京中医医院,北京100009

出　　处：《北京中医药大学学报》1997年第6期38-39,共2页Journal of Beijing University of Traditional Chinese Medicine

摘　　要：观察了实验性糖尿病大鼠血浆血管紧张素Ⅱ (ATⅡ )、C肽的变化及中药糖心宁对它们的作用。结果表明 ,ATⅡ的含量对照组高于正常组 (P <0 0 1 ) ,治疗组低于对照组 (P <0 0 1 )。C肽的含量对照组低于正常组 (P <0 0 1 ) ,治疗组高于对照组(P <0 0 1 )。ATⅡ的升高可以对心脏产生有害的作用。糖心宁可以提高C肽的含量 ,改善β细胞的功能。糖心宁可能通过多途径作用降低ATⅡ的含量 。Changes of plasma AT Ⅱ and C piptide in the rat with experimental diabetes and the effects of TCM preparation Tangxinning over them were observed. The results showed that the AT Ⅱ level of the control group was higher than the normal group ( P <0.01),and that of the treating group was lower than the control group ( P <0.01). The C piptide level of the control group was lower than the normal group ( P <0.01), and that of the treating group was higher than the control group ( P <0.01)

关 键 词：糖尿病 血浆 血管紧张素Ⅱ C肽 糖心宁 

分 类 号：R259.871[医药卫生—中西医结合] R266.715[医药卫生—中医内科学]