儿童过敏性紫癜60例临床分析  

Clinical diagnosis and treatment of 60 Children with henoch-schonlein purpura

作　　者：孙晓宝[1] 吴小平[1] 常绍光[1] 

机构地区：[1]淮南市第一人民医院儿科,安徽省淮南232007

出　　处：《中国基层医药》2008年第8期1255-1256,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的分析过敏性紫癜（HSP）患儿的临床资料，总结该病的临床特征。方法对60例HSP患儿临床表现进行总结分析。结果（1）发病年龄在3～14岁，多见于5～10岁，女性多于男性（比率为2：1），冬春季好发；以呼吸道感染为主要诱因。（2）所有患儿均有典型皮肤紫癜，累及双下肢（100％），其次是臀部（30％）、双上肢（13％）、颜面（7％）；80％以皮肤紫癜为首发症状，30％皮肤紫癜于病程中反复出现；少数以胃肠道及关节症状首发。（3）60％患儿关节受累；胃肠道症状发生率47％；肾损害发生率13％。结论HSP皮肤紫癜的发生率100％，关节症状和胃肠症状在大多患儿均可发现，紫癜性肾炎（HSPN）是其严重的并发症，肾脏受损程度直接影响HSP患儿的预后。Objective To analyze the clinical data of henoch-schonlein purpura（HSP） in children and to conclude the clinical featrues of HSP. Methods The clinical features of 60 children with HSP were analyzed. Results （ 1 ）The age of onset of all the 60 children with HSP was from 3 to 14 years old, especially from 5 to 10 years and the female patients were more than the male patients（the rate was 2：1）. Of the 60 children,they developed HSP in the four seasons, especially in the spring and winter; most of the HSP patients revealed evident predisposing factors, mainly upper respiratory infection. （2）All the patients had typical purpura. 80% had typical purpura as the presenting contaneous sign. The distribution of rash in the lower extremitices, buttock upper extremities and face was 100 % , 30 % , 13 % and 7 % . 30 % occurre, repeatedly. （3） Gastrointestinal involvement and arthritis occurred rate is 47 % and 60 %, respectively. Of all the patients, 13 % developed HSP nephritis manifested as isolated hematuria and/ or proteinuria. Conclusion HSP has its own clinical and episodic features. It is not difficult to diagnose the typical case. HSPN is its serious syndrome,it should be long-term follow-up of kidney conditions.

关 键 词：紫癜 过敏性 儿童 临床分析 

分 类 号：R72[医药卫生—儿科]