手术联合辅助治疗对局部复发性直肠癌的疗效分析  

Surgery with adjuvant therapy for locally recurrent rectal cancer

作　　者：庄华章[1] 郭云[2] 唐宗江[2] 

机构地区：[1]海口市人民医院肛肠外科,570208 [2]广西医科大学第一附属医院结直肠肛门外科

出　　处：《中华普通外科杂志》2008年第9期680-682,共3页Chinese Journal of General Surgery

摘　　要：目的探讨手术切除联合辅助治疗对局部复发性直肠癌的治疗效果。方法对1993年8月至2002年2月间收治的107例局部复发再治疗者采用不同治疗方法的临床疗效进行回顾性分析。结果手术联合辅助治疗组（A组）32例，单纯手术组（B组）37例，单独辅助治疗组（C组）38例，三组中位年龄分别为：49．3±20．7、44．4±25．4、52．9±29．1岁。A、B、C组中位生存期分别为27．8、14．6、13．7个月。A组5年生存率显著优于B组（X^2=6．862，P〈0．05）和C组（X^2=4．286，P〈0．05）。结论对于复发性直肠癌行包括手术在内的综合治疗可延长患者的生存期。Objective To explore the efficacy of treatment for locally recurrent rectal cancer after radical surgery. Methods In this study, the management of 107 patients with postoperative locally recurrence of rectal carcinoma admitted from August 1993 to February 2002 was retrospectively analyzed. Results Thirty-two cases were treated by reoperation combined with adjuvant therapy （group A ） , 37 cases underwent resection alone（ group B）,38 patients received adjuvant therapy alone （group C）. The age of these patients was 49. 3 ± 20. 7, 44.4 ± 25.4, and 52. 9 ± 29. t respectively. The median survival time after treatment was 27.8, 14. 6, and 13.7 months, respectively. The five year＇s survival of patients in group A was better than that in group B and group C significantly （ P 〈 0. 05 ）. Conclusions The aggressive surgery combined with adjuvant therapy improves the survival of the patients with locally recurrent rectal cancer after radical surgery.

关 键 词：直肠肿瘤 肿瘤复发 局部 手术 辅助治疗 

分 类 号：R686[医药卫生—骨科学]