茜草提取物对耐力训练后再力竭运动大鼠心肌组织自由基代谢、激素水平影响的实验研究  

An Experimental Study of the Effect of Rubia Cordifolia on Metabolism of Free Radical of Heart,Level of Hormone and Sporting Ability of Endurance-trained Exhausting Mice

作　　者：陈梅[1] 李峰[2] 

机构地区：[1]长安大学体育部,陕西西安710062 [2]西安建筑科技大学体育系,陕西西安710055

出　　处：《北京体育大学学报》2008年第8期1090-1092,共3页Journal of Beijing Sport University

摘　　要：目的:通过分析耐力训练后一次力竭性运动大鼠(♂)部分自由基指标的变化来探讨补充茜草提取物抗氧化、提高机体抗疲劳能力的可能机制。方法:通过建立大鼠递增大强度耐力跑台训练实验模型,测定了大鼠力竭时间、心肌织某些生化指标和抗氧化酶活性一以及血清皮质醇、醛固酮、血浆心钠素影响。结果:茜草可增加耐力运动后再力竭即刻状态下谷光甘肽过氧化物酶(GSH-Px)、锰超氧化物歧化酶(Mn-SOD)、铜、锌超氧化物歧化酶(Cu、Zn-SOD)、还原性谷胱甘肽(GSH)活性以及醛固酮和心钠素的含量;降低丙二醛(MDA)和皮质醇含量。结论:补充茜草提取物可显著提高小鼠心肌和肝脏组织抗氧化酶的活性,减轻大强度耐力训练对大鼠心肌和肝脏组织造成的脂质过氧化损伤,具有明显的抵抗脂质过氧化的功能,对小鼠运动能力的提高有良好的作用。Objectives： By building a long time and high-intensity and endurance-trained and exhausting exercise model in mice（♂）,testing the activities of GSHPx,Mn-SOD,Cu-Zn-SOD,GSH,content of MDA,serum cortisol,aldosterone,atrial natriuretic and the exhausting time,the effects of Rubia cordifolia L on metabolism of free radical of heart are studied in trained mice.The results indicate the activities of GSH-Px,Mn-SOD,Cu,Zn-SOD,GSH,aldosterone,atrial natriuretic factor in most of Rubia cordifolia L groups are higher and the content of MDA and serum cortisol is lower.Conclusion： Rubia cordifolia L can promote the mice capacity of antioxidation and reduce the content of MDA,have obvious improve great mouse＇s sports ability.

关 键 词：茜草 耐力训练 自由基 力竭 抗氧化酶 

分 类 号：G804.7[文化科学—运动人体科学]