芒果苷片薄膜包衣工艺的研究  

Study on Thin-Film Coating Process for Mangiferin Tablet

作　　者：邓家刚[1] 王志萍[1] 申文慧[1] 韦慧鲜[1] 

机构地区：[1]广西中医学院,南宁530001

出　　处：《中国药师》2008年第10期1140-1142,共3页China Pharmacist

基　　金：国家科技部"西部开发"重大项目(2004BA901A09);广西科技攻关项目(桂科攻关0592001-13)

摘　　要：目的:探讨芒果苷片薄膜包衣工艺的最佳工艺参数。方法:采用比较法和正交试验设计法,以包衣片外观合格率、硬度、增重、耐湿度、溶出度等作为考核指标,确定薄膜包衣的最佳工艺参数。结果:最佳包衣工艺参数为:包衣液浓度为13%,主机转速为12 r·min^(-1),片床温度45℃。结论:此工艺稳定可行。Objective： To optimize the conditions of thin-film coating process for mangiferin tablets. Methods： The evaluation indexes were appearance qualified rate, hardness, weight increment, humidity endurance, and dissolution rate. Thin-film coating process conditions were optimized by compare-method and orthogonal method. Results： The best process parameters were that concentration of coated solution was 13%, engine speed was 12r·min^-1, and bed temperature was 45℃. Conclusion： The process was feasible and stable.

关 键 词：芒果苷片 薄膜包衣工艺 比较法 正交设计法 

分 类 号：R283.64[医药卫生—中药学]