老年代谢综合征患者脉压与心血管重塑的关系  

Relationship between pulse pressure and cardiovascular remodeling in elderly patients with metabolic syndrome

作　　者：吴政[1] 施晓芸[1] 

机构地区：[1]福建医科大学附属协和医院干部病房,福建省福州市350001

出　　处：《实用老年医学》2008年第5期355-357,共3页Practical Geriatrics

摘　　要：目的探讨老年代谢综合征(MS)患者脉压(PP)与心血管重构(颈动脉肥厚及左室肥厚)的关系。方法用超声检测76例MS患者和51例非MS患者的颈动脉内膜中层厚度(IMT)及左室质量指数(LVMI),并分析MS患者的颈动脉肥厚、左室肥厚与PP的关系。结果(1)2组患者在血脂、血糖、体质量指数、PP、IMT及LVMI间差异均有统计学意义(P<0.05或P<0.01);(2)在MS组中,患者PP增高则颈动脉IMT及LVMI也增加,而颈动脉肥厚及左室肥厚组的PP也明显增高(P<0.01)。结论MS患者脉压增高与心血管重塑密切相关。Objective To investigate the relationship between pulse pressure （PP） and cardiovascular remodeling in elderly patients with metabolic syndrome （ MS ）. Methods Seventy-six elderly patients with MS and fifty-one healthy controls were enrolled. Blood lipid, serum glucose, body mass index （BMI）, intima-media thickness（IMT）and PP were measured. IMT, interventricular septal thickness（IVST）, left ventricular posterior wall （LVPW） and left ventricular end diastolic dimension （LVED） were measured by uhrasonography. Relationship between IMT, left ventricular mass index （LVMI） and PP were analyzed. Results PP, IMT and LVMI were significantly higher in the patients with MS than those in the controls （P 〈0. 05, P 〈0. 01 ）. In MS group, LVMI and IMT increased when PP increased （P 〈0. 05, P 〈 0. 01 ）. Conclusions There is significant relationship between PP and cardiovascular remodeling in the elderly patients with MS.

关 键 词：代谢综合征 脉压 心血管重塑 

分 类 号：R589[医药卫生—内分泌]