实验性脑死亡脑外器官变化  

Macro，micro and ultrastructural observations of pituitary, adrenal, pancreas and spleen in experimental brain death

作　　者：魏本庆 李德祥[2] 汪德文[2] 

机构地区：[1]临沂市中级人民法院,山东2760004 [2]中国医科大学法医学系,辽宁沈阳110001

出　　处：《法医学杂志》1997年第4期195-198,共4页Journal of Forensic Medicine

摘　　要：研究了原发性脑死亡垂体、肾上腺、胰腺、脾脏等脏器宏观、微观及超微结构的变化规律．结果如下：（1）胰腺腺泡酶原颗粒减少，胰岛细胞核固缩；（2）脾脏被膜下出血，脾窦扩张淤血；（3）肾上腺皮质及髓质细胞疏松，胞核浓缩；超微结构可见束状带细胞线粒体嵴消失，核质溶解；（4）腺垂体细胞核变小，胞质出现空泡，神经垂体胶质细胞增生，纤维组织排列紊乱，染色浅淡；（5）原发性脑死亡可以引起脑外器官包括垂体、肾上腺、胰腺、脾脏的形态结构变化，但远比脑组织本身的变化轻．The purpose of this study is to observe the macro,Micro and ultrastructural changes of the pituitary, adrenal, pancreas and spleen in the experimental primary brain death. The results showed: 1. Acinar zymogen granule of pancreas decreased, karyopyknosis of islet cells formed 2.dilation and blood stasis of spleen sinus happened 3.adrenocortical karyopyknosis formed, mitochondrial crista vanish.4.Pituitary karyopyknosis and cytolysis developed. 5.There was correlation between the extent of lesions And time after brain death.

关 键 词：脑死亡 脑器官 核固缩 核质溶解 死亡 

分 类 号：R339.39[医药卫生—人体生理学] R338[医药卫生—基础医学]