瑞芬太尼用于小儿先天性心脏病手术快通道麻醉  

APPLYING REMIFENTANIL TO FAST TRACK CARDIAC ANESTHESIA IN CHILDREN WITH CONGENITAL CARDIOPATHY

作　　者：吴曼[1] 邢桂英[1] 于建设[1] 秦斐[1] 朱宪明[1] 

机构地区：[1]内蒙古医学院附属医院麻醉科,内蒙古呼和浩特010050

出　　处：《内蒙古医学院学报》2008年第4期250-252,共3页Acta Academiae Medicinae Neimongol

基　　金：内蒙古自治区自然科学基金(200607010901)

摘　　要：目的：观察瑞芬太尼用于小儿先天性心脏病手术的麻醉效应及术后恢复情况。方法：择期行房间隔缺损（ASD）或室间隔缺损（VSD）修补术患儿30例，ASAⅠ-Ⅱ级，随机分为瑞芬太尼组（R组）和芬太尼组（F组）。分别于不同时间记录血流动力学参数，并采集静脉血标本测量应激激素浓度，观察术后机械通气时间及拔管时间。结果：与F组相比，R组在术中各时点血流动力学参数和应激激素浓度差异无统计学意义，（P〉0．05）。但是拔管时间及术后在ICU逗留时间R组较F组显著缩短（P〈0．05）。结论：瑞芬太尼能保持术中血流动力学的稳定，有效抑制应激反应，术后能早期拔管，适用于小儿心脏手术快通道麻醉。Objective： To evaluate the use of remifentanil analgesia in pediatric undergoing cardiac surgery, witb cardiopulmonary bypass. Methods：30 ASA Ⅰ-Ⅱ pediatric patients with atrial septal defect or simple ventricular septal defect were randomly divided into two groups： remifentanil group （group R） and fentanyl group（ group F）. The hemodynamic and stress hormone changes were recorded perioperatively. The extubation time and duration in ICU were also recorded. Results：There was no significant difference between the two groups on hemodynamic parameters and blood level of stress hormone at the same time points （ P 〉 0.05）. Tracheal extubation in group R was earlier than that in group F（ P 〈0. 05）. Duration in ICU in group R was shorter than that in group F（ P 〈0.05）. Condusion：Remifentanil could be safely and effectively used for fast track cardiac anesthesia in children with stable hemodynamics,effective inhibition of stress hormones and early extubation.

关 键 词：瑞芬太尼 小儿 心脏快通道麻醉 应激激素 

分 类 号：R971.2[医药卫生—药品]