水杨酰肼的合成工艺研究  

SYNTHESIS AND FUNGICIDAL EFFECT OF SOME DERIVATIVES OF SALICYLIC ACID HYDRAZIDE

作　　者：龚筱群[1] 陈洪超[1] 

机构地区：[1]华西医科大学药学院,成都610041

出　　处：《华西药学杂志》1997年第4期240-240,242,共2页West China Journal of Pharmaceutical Sciences

摘　　要：采用均匀设计方法，按回归方程优化肼解水杨酸甲酯合成水杨酰肼的工艺条件，结果使合成产率从86．45％提高到了94．74％。A salicyl hydrazide is a better intermediate of fungicide. It was prepared by means of the hydrazinolysis of methyl salicylate. Uniform design was adopted for arranging the synthetic technological condition of preparing a salicyl hydrazide. The synthetic technological optimization was attained by calculating, and the synthetic yield rate was raised from 86. 45% to 94. 74%.

关 键 词：水杨酰肼 合成 肼解 杀菌剂 中间体 

分 类 号：TQ225.266[化学工程—有机化工]