双歧杆菌在肿瘤基因治疗中的应用  

Application of bifidobacterimn in cancer gene therapy

作　　者：孙月丽(综述)[1] 赵擎宇(审校)[1] 

机构地区：[1]中山大学肿瘤防治中心ICU,广州510060

出　　处：《国际肿瘤学杂志》2008年第9期650-653,共4页Journal of International Oncology

摘　　要：双歧杆菌是定植于人类或某些哺乳动物肠道内的生理菌群，厌氧、无致病性，能维持肠道内环境稳定，促进机体生长，提高免疫力，具有重要的作用，受到营养学和食品学的广泛关注。近年来双歧杆菌又因重要的抗肿瘤作用和其趋厌氧性、无致病性引起医学界的重视，成为肿瘤基因治疗载体的重要研究对象。Bifidobacterium,a kind of anaerobic and nonpathogenic bacteria,is an inherent flora of human body or some mammal. It plays an important part in maintaining the stability of intestinal environment, growth promotion, and improving the immunity, etc. It attracts wide attention in nutrition and food science because of these advantages. Recently, bifidobaeterium is interested by medical science field because of its antitumor function and its anaerobic and nonpathogenie characters. It can be used as a specific gene delivery vector for cancer gene therapy.

关 键 词：肿瘤 二裂菌属 基因治疗 

分 类 号：R378.99[医药卫生—病原生物学]