指长比与冠心病的相关性研究  

RELATIONSHIP BETWEEN DIGIT RATIO AND CORONARY HEART DISEASE

作　　者：陆宏[1] 霍正浩[1] 张科静[2] 魏宁[2] 师志云[1] 彭亮[1] 党洁[1] 焦海燕[1] 

机构地区：[1]宁夏医学院医学遗传与细胞生物学教研室 [2]宁夏医学院附属医院心内科,银川750004

出　　处：《解剖学报》2008年第5期765-768,共4页Acta Anatomica Sinica

基　　金：国家自然科学基金(30260045);宁夏高等学校科学技术研究项目(JC200504)资助

摘　　要：目的研究宁夏男性指长比与冠心病的相关性。方法采用体质测量法,研究宁夏汉族男性304例(正常对照152例,冠心病患者152例)左右手指长比(2D∶3D、2D∶4D、2D∶5D、3D∶4D、3D∶5D、4D∶5D),探讨其与冠心病的相关性。结果宁夏汉族男性正常对照组与冠心病患者组指长比均值呈现2D∶3D<2D∶4D<3D∶4D<2D∶5D<4D∶5D<3D∶5D的趋势;冠心病患者组指长比均值高于正常对照组,2D∶3D(左手P<0.05)、2D∶4D有显著性差异(左手P<0.01;右手P<0.05),2D>4D的比例高于对照组;冠心病患者组指长比均值与发病年龄呈负相关(P<0.001)。结论指长比,尤其是左手2D∶4D可能是冠心病早期筛选的重要参考指标之一。Objective To investigate the relationship between the digit ratio and coronary heart disease. Methods Use anthropometry, digit length of both hands in each person was measured. Digit ratios were counted and compared between right hands and left hands, for coronary heart disease patients and controls respectively. Results （ 1 ） Our results showed the trend as 2D： 3D 〈 2D ： 4D 〈 3D ： 4D 〈 2D ： 5D 〈 4D ： 5D 〈 3D ： 5D in both groups. （2） The mean values for digit ratio was higher in the patient group than that of the control group. Significant differences in digit ratio for 2D：3D （left, P 〈 0.05） and 2D：4D（left, P 〈 0.01 ： right, P 〈 0.05 ） were abserved between patients and controls. （3） We have shown a negative relation between the digit ratio and the onset age of coronary heart disease in Ningxia Han males（ P 〈 0.001 ）. Conclusion Digit ratio, especially 2D：4D in the left hand may be one of the important early diagnosis markers for coronary heart disease.

关 键 词：指长比 冠心病 体质测量 汉族 

分 类 号：Q983[生物学—人类学]