Tribromoisocyanuric Acid and DABCO-Br as Efficient Catalysts for the Silylation of Hydroxyl Groups with Hexamethyldisilazane  

作　　者：Khodabakhsh NIKNAM Mohammad Ali ZOLFIGOL Gholamabbas CHEHARDOLI Mina DEHGHANIAN 

机构地区：[1]Department of Chemistry,Faculty of Sciences,Persian Gulf University,Bushehr 75169,Iran [2]Faculty of Chemistry,Bu-Ali Sina University,P.O.Box 4135,Hamedan 6517838683,Iran [3]School of Pharmacy,Hamedan University of Medical Sciences,65178 Hamedan,Iran

出　　处：《催化学报》2008年第9期901-906,共6页

基　　金：Supported by Bu-Ali Sina University Research Council.

摘　　要：Many primary,secondary,tertiary alcohols,and phenolic hydroxyl groups were effectively converted to their corresponding trimethylsilyl ethers using hexamethyldisilazane in the presence of catalytic amounts of tribromoisocyanuric acid and DABCO-bromine under mild conditions at room temperature with short reaction times in good to excellent yields.Excellent chemoselective silylation of hydroxyl groups in the presence of other functional groups were also observed.Many primary, secondary, tertiary alcohols, and phenolic hydroxyl groups were effectively converted to their corresponding trimethylsilyl ethers using hexamethyldisilazane in the presence of catalytic amounts of tribromoisocyanuric acid and DABCO-bromine under mild conditions at room temperature with short reaction times in good to excellent yields. Excellent chemoselective silylation of hydroxyl groups in the presence of other functional groups were also observed.

关 键 词：DABCO-溴 催化剂 催化作用 化学分析 

分 类 号：O643.3[理学—物理化学]