363例IgA肾病气阴两虚证临床和病理特点  

Clinical and pathological characteristics of 363 cases of both qi and yin deficiency syndrome of IgA nephropathy

作　　者：聂莉芳[1] 韩东彦[2] 余仁欢[1] 于大君[1] 孙红颖[1] 王洪霞[1] 林秀彬[1] 张昱[1] 徐建龙[2] 

机构地区：[1]中国中医科学院西苑医院肾病科,北京100091 [2]中国中医科学院

出　　处：《北京中医药大学学报（中医临床版）》2008年第5期1-4,共4页Journal of Beijing University of Traditional Chinese Medicine

基　　金：中国中医科学院优势病种课题(No.CACMS05Y0013)

摘　　要：目的观察IgA肾病气阴两虚证的临床及病理特点。方法对363例IgA肾病气阴两虚证患者的临床资料进行横断面调查,分析其发病情况及病理分布特点等。结果20～39岁年龄段所占的比例最大(63.6%),分别有35.0%和36.6%的患者有慢性咽炎、慢性扁桃体炎病史,尿检特点以血尿伴蛋白尿为主(占78.3%),病理类型以系膜增生性肾小球肾炎者最多,为182例(50.1%)。结论IgA肾病气阴两虚证多发于中青年,上呼吸道感染在其发病中占有重要地位,临床以血尿伴蛋白尿多见,其病理类型以系膜增生性肾小球肾炎最多,分级以Ⅲ级居多。Objective To observe the clinical and pathological characteristics of both qi and yin deficiency syndrome of IgA nephropathy. Method A cross-sectional study was conducted on the clinical materials from 363 cases of both qi and yin deficiency syndrome of IgA nephropathy, and furthermore the onsets and pathological distributive characteristics were analyzed. Result The age group 20 to 39 had the greatest proportion （63.6 %）. The patients with the history of chronic pharyngitis accounted for 35.0 % and those with the history of chronic tonsillitis for 36.6 %. Among the urine test results the most common result was hematuria accompanied by albuminuria （78.3 %）. The pathological type was mostly mesangial proliferative glomerulonephritis in the patients （182 cases, 50.1%）. Conclusion The syndrome of both qi and yin deficiency of IgA nephropathy was common in the group of middle-aged and young. The upper respiratory tract infection plays an important role in the onset of both qi and yin deficiency syndrome of IgA nephropathy. The common symptoms include hematuria accompanied by albuminuria, and the pathological type is mostly mesangial proliferative glomerulonephritis and more cases are included in Ⅲ class.

关 键 词：IGA肾病 气阴两虚证 临床特征 病理特点 

分 类 号：R256.5[医药卫生—中医内科学]