The Sensitization of Anti-Cancer Therapy by Squalene and Schisandrin Through the Modulation of DNA Damage Checkpoint Activity.  

作　　者：HiroshiNishida NaotoTatewaki YukiNakajima TetsuyaKonishi NobuoIkekawa 

机构地区：[1]NiigataUniversityofPharmacyandAppliedLifeSciences NiigataBioResrarchCenter,JAPAN

出　　处：《长春中医药大学学报》2008年第5期601-601,共1页Journal of Changchun University of Chinese Medicine

摘　　要：ATM(ataxia telangiectasia mutated)and ATR(AT and Rad3 related)protein kinases play a crucial role in cellular DNA damage responses.The inhibition of these kinases and/or following effectors lead to an abolishment of one such signal pathways termed as checkpoints.It is expectedATM（ataxia telangiectasia mutated）and ATR（AT and Rad3 related）protein kinases play a crucial role in cellular DNA damage responses. The inhibition of these kinases and/or following effectors lead to an abolishment of one such signal pathways termed as checkpoints.

关 键 词：五味子 DNA损伤 中医 肿瘤 治疗方法 

分 类 号：R282.71[医药卫生—中药学] R361[医药卫生—中医学]