肺结核合并肺毛霉菌感染的临床分析  

Clinical analysis of Tuberculosis combining with lung thread fungus infection

作　　者：孙莹[1] 孙文青[1] 赵婷婷[1] 周明香[1] 

机构地区：[1]济南市山东省胸科医院呼吸四科,250013

出　　处：《临床肺科杂志》2008年第11期1440-1441,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨肺结核合并肺毛霉菌感染的防治。方法对8例肺结核合并肺毛霉菌感染的危险因素、临床表现、诊断及治疗进行总结分析。结果8例肺结核患者经深部痰培养临床确诊为肺毛霉菌感染。用两性霉素B治疗大约4周后,6例有效,1例出现肾功能不全合并高钾血症行透析治疗,1例合并蛛网膜下腔出血死亡。结论肺毛霉菌病因临床表现无特异性,易误诊。早期诊断,规范抗结核治疗,合理应用抗生素、激素,早期应用两性霉素B脂质体是提高肺结核合并肺毛霉菌病治愈率的关键。Objective To approach prevention and cure for TB combining with lung thread fungus infection in order to decease mortality rate. Method To summarize and analyze the risk factors, clinical manifestation, diagnosis and treatment of 8 TB patients combining with lung thread fungus infection. Result 8 TB patients were clinically diagnosed as lung thread fungus infection by sputum culture, and treated with Amphotericin B bangosome for about 4 weeks. As a result ,6 patients were utilitied, 1 patient was treated with dialysis because of renal failure with hyperkalemia, and 1 patient died as combining with subarachnoid hemorrhage. Conclusion Mucormycosis is the systemic Fungal infectious disease with high mortality rate. Early treatment with Amphotericin B bangosome plays a vital role in curing TB combining with lung thread fungus infection.

关 键 词：肺结核 毛霉菌 两性霉素B脂质体 

分 类 号：R519[医药卫生—内科学] R521[医药卫生—临床医学]