T管引流术后胆汁粘度及CRP、FN、C_3的动态变化  

Denamic changes of bile viscosity CRP FN and C 3 after T tube drinage.

作　　者：兰平[1] 高根五[2] 

机构地区：[1]华西医科大学附属第一医院临床博士后流动站 [2]重庆医科大学附属第二医院

出　　处：《中国实用外科杂志》1997年第10期590-592,共3页Chinese Journal of Practical Surgery

摘　　要：为了观察胆汁中急性时相蛋白（ＡＰＰ）对胆汁流动特性的影响。利用毛细管粘度计测定胆汁相对粘度，采用单向免疫扩散法测定胆汁中Ｃ－反应蛋白（ＣＲＰ）、纤维连接素（ＦＮ）及补体Ｃ３（Ｃ３）并与胆汁引流量、体温等对照分析。发现急性梗阻性化脓性胆管炎（ＡＯＳＣ）术中胆汁粘度、ＣＲＰ、ＦＮ及Ｃ３明显高于术后各天（Ｐ＜０．０１）；而慢性胆管炎（ＣＣ）胆汁粘度、ＣＲＰ、ＦＮ、Ｃ３，术后２天达高峰（Ｐ＜０．０１）。术后ＡＯＳＣ组胆汁粘度、ＣＲＰ、ＦＮ、Ｃ３下降较ＣＣ组快；而胆管残余结石病人术后以上指标均无明显下降。体温、胆汁粘度、ＣＲＰ、ＦＮ、Ｃ３两两间呈明显正相关（Ｐ＜０．０１）。认为ＡＰＰ是引起胆汁粘度增高的重要因素；同时ＡＰＰ及粘度可用于监测胆道炎症及指导术后拔管。To observe the effect of acute phase proteins(APP)to bile rheologic charateristics.NX 3 capillary flow viscometer was used to measure bile relative viscosity,and radioimmunodiffusion(RID)was used to measure CRP FN C 3 concetration in bile,and compared with amount of biliary drainage and temperature.Results:in acute obstrcture suppurative cholangitis(AOSC),intro operative viscosity CRP FN C 3 of bile was higher than post operation(P<0 01),but in chronic cholangitis(CC),viscosity CRP FN C 3 of bile come to the highest at 2 day postoperation(P<0 01).The viscosity CRP FN C 3 of AOSC decrease was more quik than that of CC,however,that of the risidual caculus of bilary tract was not decrease postoperation.A corralation was demonstrated among the temperature viscosity CRP FN C 3 in bile.Conclution:CRP FN C 3 was one of the important factor to bile viscosity increase and stone formation.It can be used to monitor biliary inflamation and direct removed of T tube.

关 键 词：胆汁粘度 C反应蛋白 纤维连接素 补体C3 

分 类 号：R657.4[医药卫生—外科学]