门脉高压脾切除术后静脉血栓形成危险因素研究  

Study on the risk factors of portal system thrombosis after splenectomy in patient with portal hypertension

作　　者：张春旭[1] 王强[2] 郭树军[1] 

机构地区：[1]解放军第153中心医院东区普通外科,河南郑州450007 [2]第二军医大学附属长征医院普通外科,上海200003

出　　处：《肝胆胰外科杂志》2008年第5期340-342,共3页Journal of Hepatopancreatobiliary Surgery

摘　　要：目的探讨门静脉高压症患者脾切除术后门静脉系统血栓形成的危险因素。方法回顾性分析肝硬化门静脉高压症患者脾切除术300例的临床资料,选取性别、年龄、血小板计数、血小板聚集试验、门静脉血流速变化、脾脏质量及手术方式作为观察指标,对术后40例并发血栓形成的原因进行比较。结果术后门静脉系统血栓形成与血小板计数、血小板聚集试验、门静脉血流速变化及脾脏质量有关(P<0.05),与性别、年龄及手术方式无关(P>0.05)。结论脾切除术后血小板计数、血小板聚集试验、门静脉血流速变化及脾脏质量是门脉高压脾切除术后形成门静脉系统血栓的危险因素。Objective To explore the risk factors of portal system thrombosis after splenectomy in patient with portal hypertension. Methods A total of 300 patients was undergone splenectomy in the study. Portal system thrombosis occurred in 40 of 300 patients. Postoperative evaluations included age, gender, platelet count, platelet agglutination test, uhrasonography with color Doppler flow imaging of the portal system, spleen weight and operative method were recorded and reviewed. Results Platelet count, platelet agglutination test, uhrasonography with color Doppler flow imaging of the portal system and spleen quality have a close relation- ship with the development of PST （P〈0.05）. The age, sex and method of the operation did not show significant effect on the occurrence of PST （P〉0.05）. Conclusion Possible risk factors in the study are platelet count, platelet agglutination test, uhrasonography with color Doppler flow imaging of the portal system and spleen quality.

关 键 词：高血压 门静脉 脾切除术 血栓 危险因素 

分 类 号：R657.34[医药卫生—外科学] R654.3[医药卫生—临床医学]