血浆蛋白对生物材料细菌黏附的影响(英文)  

Influence of plasma protein on bacterial adhesion to biomaterials

作　　者：李艳星 熊素华 赵玉明 黄云超[2] 

机构地区：[1]咸宁市中心医院胸心外科,湖北省咸宁市437100 [2]昆明医学院第三附属医院胸心外科,云南省昆明市650101

出　　处：《中国组织工程研究与临床康复》2008年第36期7195-7198,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：云南省应用基础研究基金资助项目(2000CO11OM);云南省教委科研基金资助项目(9912206);云南省中青年后备人才培养基金资助项目 (2000YPI0)~~

摘　　要：生物材料植入感染是生物材料临床应用所面的严重问题,极大地限制着心血管生物材料临床应用和推广,而生物材料细菌黏附是心血管生物材料植入感染的起始动因。因此,防止生物材料细菌黏附是防治生物材料为中心感染的重要环节。研究发现,人体血浆蛋白对生物材料细菌黏附有重要影响,有的血浆蛋白抑制材料上细菌黏附,有的促进材料上细菌黏附。研究血浆蛋白与生物材料细菌黏附关系为防治生物材料为中心感染的发生具有重要意义。Implant-associated infection is a serious problem in the clinical application of biomaterials, which greatly restricts the generalization of cardiovascular biomaterials, while bacterial adhesion is the initial cause for implant-associated infections of cardiovascular biomaterials. Therefore, the prevention of bacterial adhesion to the biomaterials plays a crucial role in the cure of biomaterial center infection. It has reported that human plasma protei influences the bacterial adhesion to biomaterials. Some plasma proteins inhibit bacterial adhesion, whereas some promote it. Study on the correlation between plasma protein and bacterial adhesion to the hiomaterials is of great importance in the prevention and cure of biomaterials center infection.

关 键 词：血浆蛋白 细菌 生物材料 表面黏附 

分 类 号：R318.08[医药卫生—生物医学工程]