冠心病痰瘀证候血脂指标的Meta分析  

Meta Analysis on the Blood Fat of phlegm Stasis Syndrome of coronary heart disease

作　　者：袁肇凯[1] 田松[1] 黄献平[1] 胡志希[1] 孙贵香[1] 陈清华[1] 莫莉[1] 简维雄[1] 

机构地区：[1]湖南中医药大学,湖南长沙410007

出　　处：《云南中医学院学报》2008年第5期1-8,共8页Journal of Yunnan University of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(30271574);教育部博士点基金(20050541005);云南省教育厅重点项目(04A039)

摘　　要：目的：研究血脂变化在冠心病痰瘀辨证中的作用。方法：采取Meta分析的方法对相关文献中冠心病“痰浊证”、“衄瘀证”患者和“正常对照者”血脂含量进行综合分析。结果：冠心病患者TC含量血瘀证组比正常对照组高1．644—0．776倍标准差，痰浊证组比正常对照组高2．708～0．331倍标准差；TG含量血瘀证组比正常对照组高1．219～0．332倍标准差，痰浊证组比正常对照组高1．329—0．536倍标准差；HDL—C含量血瘀证组比正常对照组低0．278～1．559倍标准差，痰浊证组比正常对照组低0．445～1．262倍标准差；LDL—C含量血瘀证组比正常对照组高1．607～0．179倍标准差，痰浊证组比正常对照组高1．932～0．342倍标准差。森林图结果显示，冠心病患者血瘀证和痰浊证的TC、TG、LDL—C的含量与正常对照组相比均有显著差异，而HDL—C含量均无显著差异。结论：冠心病血瘀证和痰浊证患者血脂含量均有一定变化，其中TC、TG、LDL—C的含量的变化可以作为冠心病痰瘀辨证的客观指标。Objective： to study the functions of the alternation of blood fat in phlegm Stasis Syndrome of coronary heart disease. Methods： to adopt the Meta analysis to have a comprehensive analysis on the phlegm stasis of coronary heart disease mentioned in the literature, the patients with blood stasis and the content of blood in the normal collators. Results： the TC content the patients with coronary heart disease in the blood stasis group is 1. 644 -0. 776 times in standard deviation higher than that in the normal comparison group, Phlegm turbid group is 2. 708 ~ 0. 331times in standard deviation higher than that in normal comparison group; the Blood stasis group of TC content is 1. 219 - 0. 332 times in standard deviation higher than that in the normal group, and the phlegm turbid stasis group is 1. 329 - 0. 536 times in standard deviation higher than that in the normal group ; blood stasis group of HDL- C content is 0. 278 - 1. 559 times in standard deviation lower than that in the normal group, and phlegm turbid group is 0. 445 - 1. 262times in standard deviation lower than that in the normal group ; blood stasis group of LDL - C content is 1. 607 - 0. 179 times in standard deviation higher than that in the normal group, and phlegm turbid group is 1. 932- 0. 342times in standard deviation higher than that in the normal group. The forest graphics showed the content of TC, TG and LDL - C in the patients with blood stasis of coronary heart disease and phlegm turbid syndrome had striking differences, and while that of HTD - C had no obvious differences. Conclusion ： the blood fatcontent of the patients with coronary heart disease has a certain change in blood stasis group and phlegm turbid syndrome group, and of them, the change the content of TC, TG and LDL - C can be used for the index to differentiate blood stasis and phlegm turbid syndrome of coronary heart disease.

关 键 词：冠心病 证候 血脂 META分析 森林图 

分 类 号：R256.22[医药卫生—中医内科学]