栽培黄藤药材的化学成分研究  

Chemical Constituents of Cultivated Fibraurea recisa Pierre

作　　者：张慧颖[1,2] 李智敏[3] 张森[1] 蔡传涛[4] 饶高雄[1,3] 

机构地区：[1]云南中医学院,云南昆明650200 [2]曲靖医学高等专科学校,云南曲靖655000 [3]云南省农业科学院药用植物研究所,云南昆明650231 [4]中国科学院西双版纳热带植物园,云南昆明650231

出　　处：《云南中医学院学报》2008年第5期28-31,共4页Journal of Yunnan University of Traditional Chinese Medicine

基　　金：国家发改委高技术产业化西部专项"珍稀天然药用植物大黄藤人工培育与产业化示范工程"

摘　　要：目的:研究栽培黄藤(Fibraurea recisa Pierre.)药材的化学成分。方法:化学成分用溶剂提取后以色谱方法分离,经波谱分析鉴定结构。结果:分离鉴定了巴马汀(Palmatine,1)、药根碱(Jatrorrhizine,2)、小檗碱(Berberine,3)、非洲防己碱(Columbamine,4),四氢巴马汀(Terahydropalmatine,5),罗默碱(Roe-merine,6)、黄藤内酯(Fibraurin,7)、Fibleucin(8)、齐墩果酸(Oleanolic acid,9)、β-谷甾醇(β-sitoster-ol,10)和胡萝卜苷(Daucosterol,11)共11个化合物。结论:栽培和野生黄藤药材化学成分的结构类型和主成分一致,均以巴马汀(1)和黄藤内酯(7)为主。化合物5-6、8-11为首次从黄藤中分离得到。Objective： To study the chemical constituents of cultivated Fibraurea recisa Pierre. , a folk medicine is widely used in the Yunnan Province. Method ： The chemical constituents of cultivated Fibraurea recisa Pierre. were extracted with ethanol, then were isolated by chromatography. Their structures were elucidated based on the physicochemical property and spectrum analysis. Result： Eleven compounds were isolated and elucidated as palmatine （ 1 ）, jatrorrhizine （ 2 ）, berberine （ 3 ）, columbamine （ 4 ）, terahydropalmatine （ 5 ）, roemerine （6）, fibraurin （7）, fibleucin （8）, oleanolic acid （9）, 15-sitosterol （10）and daucosterol （11）. Conclusion： The chemical constituents of wild and cultivated Fibraurea recisa Pierre. have same structure type, and have palmatine （ 1 ） and fibraurin （7） as major components in both of them. Compounds 5 - 6, 8 - 11 were isolated from the rattan of Fibraurea recisa for the first time.

关 键 词：黄藤 人工栽培 化学成分 

分 类 号：R284.2[医药卫生—中药学]