广藿香挥发油包合工艺研究  

Study on Inclusion Technology for Volatile Oil of Pogostemon Cablin

作　　者：王瑞海[1] 刘丽梅[1] 陈琳[1] 陈韩英[2] 杨立新[3] 王维浩[3] 刘凤华[4] 许剑琴[5] 

机构地区：[1]中国中医科学院中医基础理论研究所,北京100700 [2]石河子大学药学院,新疆石河子832000 [3]中国中医科学院中药研究所,北京100700 [4]北京农学院,北京102206 [5]中国农业大学,北京102206

出　　处：《中国中医药信息杂志》2008年第10期49-51,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：北京市科技计划课题(Y0705003041631)

摘　　要：目的筛选二类中兽药畜禽抗应激颗粒中广藿香挥发油包合的最佳工艺。方法采用单因素考察法对广藿香挥发油包合前溶解的乙醇浓度、乙醇用量进行考察。采用L9(34)正交设计法对挥发油包合过程中各因素进行考察。结果广藿香挥发油最佳包合工艺为:挥发油用95%乙醇按1:20(mL/mL)的比例溶解,油:β-环糊精(β-CD)为1:8,β-CD配成10%的浓度,在40℃超声池中,超声包结2.0h。结论该工艺稳定,质量可控。Objective To optimize extraction technology for volatile oil of Pogostemon cablin in the second traditional veterinary drugs anti-stress granule. Methods The single factor was used to investigate the concentration and amount of the ethanol before inclusion of volatile oil. The L9（3^4） orthogonal design was used to optimize the factors in the process of inclusion. Results The optimal of technology method was that volatile oil was dissolved with 95% EtOH by 1 ： 20 （mL/mL）, the ratio of oil and β-CD was 1 ： 8, 13 -CD was prepared the concentration of 10%, ultrasound pool was at 40℃, 2.0 h. Conclusion The optimized process is stable and adjustable quality.

关 键 词：畜禽抗应激颗粒 广藿香挥发油 包合3-艺 

分 类 号：R283.5[医药卫生—中药学]