柴胡止血液对人置器后子宫异常出血者子宫内膜组织白介素-1β的影响  

Effect of Chaihu Zhixueye to Contents of IL-1β in Women Endometrium Tissues with Intrauterine Device

作　　者：徐薇[1] 陈钢[1] 朱蔓佳[1] 赵欣[1] 潘霞[1] 

机构地区：[1]成都中医药大学基础医学院,成都四川610075

出　　处：《成都中医药大学学报》2008年第3期25-27,共3页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(批准号:30171134);国家自然科学基金资助项目(批准号:30772703)

摘　　要：目的:研究柴胡止血液治疗宫内节育器所致子宫异常出血症的机理。方法:观察了柴胡止血液对置IUD子宫异常出血者子宫内膜组织白介素-1β含量的影响,并与中药归脾丸以及西药消炎痛进行比较。结果:柴胡止血液能够降低置IUD子宫异常出血者子宫内膜组织白介素-1β的含量,其中大剂量效果最好,与空白组比较P<0.05。结论:柴胡止血液可能通过改善子宫局部组织白介素-1β的活性,促进子宫内膜组织的修复,从而治疗置IUD所致子宫异常出血。Objective： to clarify the mechanism of Chaihu Zhixueye to uterine metrorrhagia due to IUD. Methods： to observe the effects of Chaihu Zhixueye on IL - 1β in women with IUD, and compared its effects with Guipiwan group and Indomethaein group. Results： Compared to the blank group, Chaihu Zhixueye can reduce the contents of IL-1β, especially the max dose group and the mid dose group （ P 〈0.05 ） . ConsuLts： Chaihu Zhixueye can cure uterine metrorrhagia with IUD through reguLate the activity of IL -1β, promoting the renovation of endometrium tissues.

关 键 词：柴胡止血液 宫内节育器(IUD) 白介素-1β(IL-1β) 

分 类 号：R271.11[医药卫生—中医妇科学] R731.9[医药卫生—中医学]