丹参对外周血中性粒细胞和单核细胞的调整作用  

MODULATION OF HUMAN NEUTROPHIL AND MONO CYTE CHEMOTAXIS AND SUPEROXIDE RESPONSES BY SALVIA MILTIO RRHIZA BUNGE(SM)

作　　者：王潮临[1,2] Arsalan Kharazmi Viggo Faber 

机构地区：[1]广西医科大学病理生理学教研室 [2]丹麦哥本哈根大学医院临床微生物部

出　　处：《广西医科大学学报》1997年第3期9-11,共3页Journal of Guangxi Medical University

基　　金：中丹科技合作项目

摘　　要：研究丹参对外周血中性粒细胞和单核细胞的化学趋化和超氧化物产物的影响。结果表明：丹参能明显增加两种细胞的超氧化物的产生；并对两种细胞的化学趋化有明显的抑制作用，丹参能调整中性粒细胞的氧化过程（呼吸爆发），参与化学趋化作用、炎症过程和增强中性粒细胞的杀菌能力。The effects of Chinese medicinal herb SM on human peripheral blood neutrophil and monocyte chemotaxis and superoxide responses were studied.The results showed that SM enhanced significantly the superoxide production of both cells.On the other hand,the chemotaxis activity of these two types of cells was inhibited significantly by SM.Thus,SM can modulate the oxidative burst response of the neutrophils.It also plays a regulatory role on the chemotactic process,the anti inflammatory response and the microbicidal function on the neutrophils.

关 键 词：丹参 化学趋化 超氧化物 中性粒细胞 单核细胞 

分 类 号：R962[医药卫生—药理学] R931.71[医药卫生—药学]