气-质联用分析北柴胡炮制前后超临界二氧化碳萃取物  

Study on SFE-CO2 extract from Bupleurum chinense Dc.by GC-MS

作　　者：许腊英[1] 梅静[1] 李凯[1] 陈绍文[1] 

机构地区：[1]湖北中医学院药学院,湖北武汉430061

出　　处：《中国医院药学杂志》2008年第19期1657-1659,共3页Chinese Journal of Hospital Pharmacy

基　　金：湖北省科学技术委员会攻关项目(编号:2002AA304A04)

摘　　要：目的:探讨北柴胡炮制前后超临界提取物的成分变化。方法:采用气质联用(GC-MS)分析炮制前后北柴胡的超临界二氧化碳(SFE-CO2)萃取物。结果:从炮制前后北柴胡超临界二氧化碳萃取物中鉴定出38种成分。在相对含量较高的成分中,北柴胡炮制后,8种成分相对含量明显下降,7种成分相对含量明显上升。结论:炮制后,北柴胡低沸点成分有下降趋势,高沸点成分有上升趋势。OBJECTIVE To analyze the chemical constituents of the SFE-CO2 extracts from Bupleurum chinense Dc. METHODS The chemical constituents of the volatile oil extracted by SFE-CO2 were separated and identified by GC-MS. RESULTS 38 kinds of constituents were identi fled from Bupleurum chinense Dc. and its roasted products. The relative contents of 8 kinds of constituents from the processing products decreased and 7 kinds of constituents increased. CONCLUSION In the processed products, the relative contents of some low-boiling point constituents decreased but some higher boiling point oils incre osed.

关 键 词：北柴胡 炮制 气-质联用 超临界二氧化碳 

分 类 号：R917[医药卫生—药物分析学]