参附注射液早期全程干预对严重脓毒血症患者器官功能的影响  

Shenfu Injection Early Intervention on the Organ Function with Severe Sepsis

作　　者：孙淑荣[1] 莫霄云[1] 马春林[1] 

机构地区：[1]广西中医学院第一附属医院,南宁530023

出　　处：《中国中医急症》2008年第10期1392-1393,共2页Journal of Emergency in Traditional Chinese Medicine

基　　金：广西壮族自治区卫生厅资助课题(NoZ2007109)

摘　　要：目的观察参附注射液对严重脓毒血症患者器官功能的影响。方法将严重脓毒血症患者60例随机分为治疗组与对照组,均根据药敏结果选用抗生素、早期液体复苏、纠正酸中毒等基础治疗及积极后续器官功能支持治疗,治疗组早期全程加用参附注射液。结果治疗组在稳定血压方面有明显作用,能显著减少血管活性药物的使用,且治疗组中需再次复苏者较对照组明显减少,复苏治疗后治疗组患者ALT、AST、Cr与对照组相比差异有显著性。结论参附注射液全程干预能提高严重脓毒血症患者对后续治疗的敏感性,并减轻对重要脏器功能的损害,从而降低其死亡率。Objective： To investigate the Shenfu Injection effection on patients organ function with severe sepsis. Methods： 60 patients with severe sepsis were randomly divided into the treatment group and the control group which are treated with antibiotic in accordance with antibiotic susceptibility results, early fluid resuscitation, and correct acidosis, and active follow - up support for organ function. The treatment group used Shenfu Injection early. Results： In the treatment group, had significant effect on stability blood pressure, significantly reduced the vasoactive drug use, and compared to those required to recover the control group decreased significantly. The treatment group with ALT, AST, Cr compared with the control group there were significantly different. Conclusion： Shenfu lnjection can improve the whole intervention in patients with severe sepsis of the sensitivity of follow -up treatment, and mitigation of damage to important organs function , thereby reducing the mortality rate.

关 键 词：严重脓毒血症 参附注射液 器官功能 

分 类 号：R631[医药卫生—外科学]