急性肾损伤早期生物标志物研究进展  

Early Detection of Acute Kidney Injury with New Biomarkers

作　　者：薛淑英[1] 于帮旭[2] 王继华[1] 周兴鹏[1] 陈伟[1] 牟志芳[1] 

机构地区：[1]山东省胶南市人民医院ICU,山东胶南266400 [2]青岛大学医学院附属医院ICU,山东青岛266003

出　　处：《中国现代医生》2008年第27期53-55,58,共4页China Modern Doctor

摘　　要：急性肾损伤是指发生急性肾功能异常,它概括了从肾功能微小改变到最终肾衰竭整个过程。对急性肾衰竭早期诊断和治疗具有更积极的意义。寻找能早期诊断和预测AKI的生物标志物是目前的关键。本文就近年来所研究的几种标志物作一综述。Acute kidney injury（AKI） has recently become the preferred term to describe the syndrome of acute renal failure（ARF） with ＇failure＇ or ＇ARF＇. This change will facilitate an expansion of the underlying pathophysiology and also facilitate definitions of AKI, which al- low comparisons among clinical trials of patients with similar duration and severity of illness. This review will cover the need for early detection of AKI and the role of urinary and plasma biomarkers, including enzymuria. New biomarkers are essential to change the dire prognosis of this common condition.

关 键 词：急性肾损伤 急性肾功能衰竭 生物标志物 

分 类 号：R692[医药卫生—泌尿科学]