麻杏石甘汤中抗新城疫病毒有效成分的研究  

Effect on Anti-Newcastle Disease Virus Action Examination of Maxingshigan Decoction Compositions

作　　者：崔斓斓[1] 李吉轩 齐仁立[1] 刘小匆 梁建军[1] 张慧茹[1] 

机构地区：[1]河南工业大学,郑州450000 [2]乾元浩生物股份有限公司郑州生物药厂,郑州450000 [3]广州天地实业有限公司,广州510000

出　　处：《中国农学通报》2008年第10期35-38,共4页Chinese Agricultural Science Bulletin

摘　　要：新城疫是由新城疫病毒引起的禽传染性疾病。麻杏石甘汤方剂对目前生产中常发的呼吸道疾病有明显的治疗作用,也有抗病毒和抑菌作用。通过对麻杏石甘汤中4味药物的不同剂量比例组方,采用煎煮的方法提取药物有效成分。测定提取液对鸡胚的最大致死浓度和对红细胞的凝集作用;以药液的不同浓度直接作用于病毒,接种鸡胚检验病毒滴度的变化,观察发现8种配方都有抑制病毒的作用,其中麻黄是发挥抗病毒作用的主要成分。药物对病毒的抵抗作用与药物本身对红细胞的凝集作用没有直接的联系。Newcastle disease is one of poultry infectious diseases caused by Newcastle disease virus. Maxingshigan Tang has the obvious therapeutic effects to the respiratory disease, also has the function of antivirus and the bacteriostasis. By four different doses of the medicine group of Maxingshigan Tang, using the decoction method extracted the medicine active ingredients. By determining the extract to the chicken embryo’s maximum lethal concentration and hemagglutination. By different medicine liquor concentration direct action in virus, inoculate embryo determine the change of virus titer, found that all 8 compoundings have the effect of antivirus, and Mahuang is the essential component. Medicine has no directly relation in both antivirus and hemagglutination.

关 键 词：麻杏甘石汤 鸡新城疫病毒 鸡胚法 抗病毒作用 

分 类 号：S853.23[农业科学—临床兽医学]