灰阶超声造影在甲状腺结节诊断中的应用研究  

Qualitative evaluation of thyroid nodules with gray-scale contrast-enhanced ultrasound

作　　者：张秀芳[1] 洪玉蓉[1] 鲍晓峰[1] 刘学明[1] 罗志艳[1] 陈娟娟[1] 

机构地区：[1]浙江大学医学院附属第二医院超声科,浙江杭州310009

出　　处：《浙江大学学报（医学版）》2008年第5期515-518,共4页Journal of Zhejiang University(Medical Sciences)

基　　金：浙江省教育厅项目(20061441)

摘　　要：目的:研究甲状腺良恶性结节的灰阶超声造影表现。方法:对35例患者的40个甲状腺结节术前行常规超声和灰阶超声造影检查,术后获取病理诊断。结果:良性结节15个,恶性结节25个。良性实性结节超声造影主要表现为型增强模式;恶性结节36%(9/25)表现为型,24%(6/25)表现为型,40%(10/25)表现为型。4个良性囊性结节超声造影表现为囊性部分均无增强,实性部分2个有弥漫增强,2个无增强。结论:灰阶超声造影能反映甲状腺结节的灌注情况,整个无增强或中央区无增强的实性结节可能为恶性。Objective： To assess the feasibility of gray-scale contrast-enhanced ultrasound for characterizing thyroid nodules. Methods： Forty thyroid nodules from 35 patients were studied both by conventional techniques and gray-scale contrast-enhanced ultrasound. Of the nodules examined,15 were benign and 25 malignant. The enhancement of echogenicity was evaluated. The diagnosis was confirmed by surgical biopsy and histopathological examination. Results： The study using gray-scale contrast-enhanced ultrasound showed absent contrast-enhancement in 9 of 25 malignant nodules and 1 of 11 benign solitary nodules; intense enhancement in 6 of 25 malignant nodules,with perfusion defect in the center; diffuse faint enhancement in 10 of 25 malignant nodules and 10 of 11 benign solitary nodules. Benign cystic nodules all showed absent enhancement in the cystic components and 2 of 4 intense enhancement in the solitary components. Conclusions： Gray-scale contrast-enhanced ultrasonography imaging may be a useful tool for evaluating the perfusion of thyroid nodules. Solitary nodules showing absent enhancement or intense enhancement with absent enhancement in the nodular center may suggest malignant.

关 键 词：甲状腺结节/超声检查 甲状腺肿瘤/超声检查 造影剂 诊断 鉴别 超声检查/方法 

分 类 号：R445.1[医药卫生—影像医学与核医学]